| Type | Description |
|---|---|
| Definition | sphingomyelin phosphodiesterase acid like 3B |
| Date | Results | Publications |
|---|---|---|
| 2021-02-13 13:25:00 | Phosphodiesterase SMPDL3B Gene Expression as Independent Outcome Prediction Marker in Localized Prostate Cancer. | 32575490 |
| 2021-01-23 12:57:00 | Modulation of radiation-induced damage of human glomerular endothelial cells by SMPDL3B. | 32293077 |
| 2019-07-13 11:14:00 | Study reports that SMPDL3b excess, as observed in podocytes in diabetic kidney disease, impairs insulin receptor isoform B-dependent pro-survival insulin signaling by interfering with insulin receptor isoforms binding to caveolin-1 in the plasma membrane. | 31217420 |
| 2018-05-05 10:38:00 | Glomerular immunoreactivity and urinary excretion of SMPDL3b in proteinuric nephrotic syndrome patients decreased compared with controls. | 29081073 |
| 2017-09-02 12:35:00 | These results demonstrate that radiation injury induces early cytoskeletal remodeling, down-regulation of SMPDL3b, and elevation of cellular ceramide levels. Overexpression of SMPDL3b and pretreatment with rituximab confer a radioprotective effect in cultured podocytes. | 27836988 |
| Type | IDs |
|---|---|
| Synonymous | ASML3B |
| Gene |
UniProtKB-ID:
ASM3B_HUMAN,
B4DEC6_HUMAN,
B4DW34_HUMAN
UniprotKB:
Q92485,
B4DEC6,
B4DW34
UniParc:
UPI00017A81D7,
UPI00004700F5,
UPI00017A6D25,
UPI000006FB01
EMBL:
CH471059,
AK301349,
AK293566,
Y08134,
BC014444,
AK316500,
AL512288
Ensembl:
ENSG00000130768
KO:
hsa:27293
|
| Nucleutide sequences |
EMBL-CDS:
CAA69328.1,
BAH14871.1,
AAH14444.1,
EAX07721.1,
BAG57037.1,
BAG62896.1
Ensembl_TRS:
ENST00000373888,
ENST00000373894
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000362995,
ENSP00000363001
RefSeq:
NP_001291508.1,
XP_011539562.1,
NP_001009568.1,
NP_055289.2,
XP_011539561.1
|
| Others |
UniRef100:
UniRef100_Q92485,
UniRef100_B4DW34,
UniRef100_B4DEC6
UniRef90:
UniRef90_Q92485
UniRef50:
UniRef50_Q92485
UniGene:
Hs.123659
CCDS:
CCDS30656.1,
CCDS30655.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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