| Type | Description |
|---|---|
| Definition | tumor necrosis factor receptor superfamily, member 12a |
| Date | Results | Publications |
|---|---|---|
| 2020-11-28 13:16:00 | Norcantharidin protects against renal interstitial fibrosis by suppressing TWEAK-mediated Smad3 phosphorylation. | 32979359 |
| 2020-09-26 13:04:00 | The TNF-like weak inducer of the apoptosis/fibroblast growth factor-inducible molecule 14 axis mediates histamine and platelet-activating factor-induced subcutaneous vascular leakage and anaphylactic shock. | 31679818 |
| 2020-07-25 11:41:00 | These results suggest that Fn14 deficiency protects mice from experimental atopic dermatitis, involving the attenuation of inflammatory responses and keratinocyte apoptosis. In the context of atopic dermatitis-like inflammation, TWEAK modulates keratinocytes via a TNFR1-mediated pathway. | 31515807 |
| 2020-07-25 11:36:00 | FN14 deficiency resulted in better cardiac performance, less myocardial inflammation, fibrosis, and cardiac damage in a model of autoimmune myocarditis. | 31212034 |
| 2020-02-01 12:27:00 | Fn14 may be a potential target for the therapeutic treatment of peripheral neuropathic pain. | 30976982 |
| Type | IDs |
|---|---|
| Synonymous | AI255180, C87282, Fn14, HPIP, TWEAK-R, TweakR |
| Gene |
UniProtKB-ID:
TNR12_MOUSE,
E9PZT5_MOUSE
UniprotKB:
Q9CR75,
E9PZT5
UniParc:
UPI0001AB178D,
UPI00000221B1
EMBL:
BC025860,
AK005382,
AC154766,
AF156164,
AK005530,
AK160136
Ensembl:
ENSMUSG00000023905
KO:
mmu:27279
|
| Nucleutide sequences |
EMBL-CDS:
BAE35650.1,
AAH25860.1,
BAB24101.1,
AAF07882.1,
BAB23989.1
Ensembl_TRS:
ENSMUST00000024698,
ENSMUST00000167059
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000024698,
ENSMUSP00000131574
RefSeq:
NP_038777.2,
NP_001155218.1
|
| Others |
UniRef100:
UniRef100_Q9CR75,
UniRef100_E9PZT5
UniRef90:
UniRef90_E9PZT5,
UniRef90_Q9CR75
UniRef50:
UniRef50_Q9CR75,
UniRef50_I3L7R8
UniGene:
Mm.28518
CCDS:
CCDS28456.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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