SIT1 - signaling threshold regulating transmembrane adaptor 1-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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27240 SIT1

基因描述

Type	Description
Definition	signaling threshold regulating transmembrane adaptor 1

研究结论

Date	Results	Publications
2012-02-04 10:04:00	SIT as an important modulator of TCR-mediated signaling that regulates T-cell activation, homeostasis and tolerance	21957439
2009-03-25 21:36:00	Observational study of gene-disease association. (HuGE Navigator)	19204726

名称对应

Type	IDs
Synonymous	SIT, SIT-R
Gene	UniProtKB-ID: SIT1_HUMAN UniprotKB: Q9Y3P8 UniParc: UPI0000073C61 EMBL: BC102029, AK314758, AJ010059, AJ271888, AL357874, BC104491, BC107484, CH471071 Ensembl: ENSG00000137078 KO: hsa:27240
Nucleutide sequences	EMBL-CDS: BAG37296.1, CAB41504.1, EAW58370.1, AAI02030.1, AAI07485.1, AAI04492.1, CAC81313.1 Ensembl_TRS: ENST00000259608
Protein sequencees	Ensembl_PRO: ENSP00000259608 RefSeq: NP_055265.1
Others	UniRef100: UniRef100_Q9Y3P8 UniRef90: UniRef90_Q9Y3P8 UniRef50: UniRef50_Q9Y3P8 UniGene: Hs.88012 CCDS: CCDS6582.1

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Pubmed编号	文献信息	发表日期	相关基因
32296183	A reference map of the human binary protein interactome. Nature Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G CotÃ© , Meaghan Daley , Steven Deimling , Alice Desbuleux , AmÃ©lie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , IstvÃ¡n A KovÃ¡cs , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat TaÅan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood	2020-04-01	-
29987050	Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy. Proc. Natl. Acad. Sci. U.S.A. Tengfei Xiao , Wei Li , Xiaoqing Wang , Han Xu , Jixin Yang , Qiu Wu , Ying Huang , Joseph Geradts , Peng Jiang , Teng Fei , David Chi , Chongzhi Zang , Qi Liao , Jonathan Rennhack , Eran Andrechek , Nanlin Li , Simone Detre , Mitchell Dowsett , Rinath M Jeselsohn , X Shirley Liu , Myles Brown	2018-07-31	-
30585266	The intracellular NADH level regulates atrophic nonunion pathogenesis through the CtBP2-p300-Runx2 transcriptional complex. Wentao Zhang , Ning Duan , Qian Zhang , Tao Song , Zhong Li , Xun Chen , Kunzheng Wang	2018-01-01	-
26439863	Cell Surface Proteomic Map of HIV Infection Reveals Antagonism of Amino Acid Metabolism by Vpu and Nef. Cell Host Microbe Nicholas J Matheson , Jonathan Sumner , Kim Wals , Radu Rapiteanu , Michael P Weekes , Raphael Vigan , Julia Weinelt , Michael Schindler , Robin Antrobus , Ana S H Costa , Christian Frezza , Clary B Clish , Stuart J D Neil , Paul J Lehner	2015-10-14	-
23648065	Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan. Cancer Sci. Siew-Kee Low , Suyoun Chung , Atsushi Takahashi , Hitoshi Zembutsu , Taisei Mushiroda , Michiaki Kubo , Yusuke Nakamura	2013-08-01	LOC100129345, LOC100129620, SNAP25-AS1, LOC100131425, LOC100131680, GNG12-AS1, MIR2113, LOC100420587, LOC100421527, LOC100505995, LOC100506098, LOC101928667, LOC101929200, LOC101929241, LOC102723507, VAV3, AGR2, ME3, PRSS23, ATP6V1G3, CHODL, LOC151121, DAB2IP, ADAMTS18, SRSF10P2, EBF1, ESRRG, GSX1, GPC5, MLXIP, FOXI1, FLNB, KIAA0922, KAZN, LRRC8B, OSBP2, FSHR, ALPL, AKNAD1, GALC, ULK3, LRIG1, FAM50B, SIT1, PRTG, LOC284294, SCARA5, GRM7, HOXC13, MACC1, FTCDNL1, RPS16P2, MATN2, RPL36AP45, CRYL1, PDE4D, HMP19, SERPINE2, PLCG2, TMEM106B, FGD6, ERGIC1, ALPK3, RXRA, PRDM1, LHPP, CSMD1, RPL13AP3, LOC651644, SLC13A1, TRA, TNFRSF1A, ZNF236, SPEF2, DENND1C, WLS, CMIP, APOL3, PTPN5, GAS7, RAB9BP1, ARHGAP18, NCOR2, ZNF536, ARHGAP44, HS3ST2
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
21957439	The transmembrane adaptor protein SIT inhibits TCR-mediated signaling. PLoS One BÃ¶rge Arndt , Tina Krieger , Thomas Kalinski , Anja Thielitz , Dirk Reinhold , Albert Roessner , Burkhart Schraven , Luca Simeoni	2011-01-01	-
20458337	MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis. Immunol. Cell Biol. Sonja I Buschow , Bas W M van Balkom , Marian Aalberts , Albert J R Heck , Marca Wauben , Willem Stoorvogel	2010-05-11	-
19204726	Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimer's disease. Mol Psychiatry J Chapuis , D Hot , F Hansmannel , O Kerdraon , S Ferreira , C Hubans , C A Maurage , L Huot , F Bensemain , G Laumet , A M Ayral , N Fievet , J J Hauw , S T DeKosky , Y Lemoine , T Iwatsubo , F Wavrant-DevriÃ¨ze , J F Dartigues , C Tzourio , L BuÃ©e , F Pasquier , C Berr , D Mann , C Lendon , A AlpÃ©rovitch , M I Kamboh , P Amouyel , J C Lambert	2009-11-01	-
18029348	Toward a confocal subcellular atlas of the human proteome. Mol Cell Proteomics Laurent Barbe , Emma Lundberg , Per Oksvold , Anna Stenius , Erland Lewin , Erik BjÃ¶rling , Anna Asplund , Fredrik PontÃ©n , Hjalmar Brismar , Mathias UhlÃ©n , Helene Andersson-Svahn	2008-03-01	-

研究热度

发表文献

热点单位

排名	科研单位	文献
1	Dana-Farber Cancer Institute	2
2	Immunomodulation Laboratory of the Institute for Immunology	2
3	Genomics Institute of the Novartis Research Foundation	2
4	Institute for Research in Biomedicine (IRB Barcelona)	1
5	Lunenfeld-Tanenbaum Research Institute (LTRI)	1

热点人员

排名	研究人员	文献
1	B Schraven	4
2	E Bruyns	3
3	H Kirchgessner	2
4	Ursula Skalska	2
5	Mark Ketteman	2

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