| Type | Description |
|---|---|
| Definition | Rho guanine nucleotide exchange factor 16 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:16:00 | FYN is required for ARHGEF16 to promote proliferation and migration in colon cancer cells. | 32811808 |
| 2019-01-19 12:20:00 | Authors found that ARHGEF16 mRNA level was upregulated in U87 cells overexpressing GLI2A relative to control cells. GLI2 binds to the ARHGEF16 promoter and activates gene transcription. Glioma cells U87 and U118 overexpressing ARHGEF16 showed enhanced migration and proliferation. | 30305138 |
| 2011-11-15 14:54:00 | Sixty-four novel structural analogues of Y27632 were synthesized and tested for their ability to persistently inhibit the transformation of NIH3T3 cells by Rho guanidine exchange factor 16 (ARHGEF16) or Ras. | 19707205 |
| 2011-11-15 12:42:00 | These data suggest that HPV16 E6, Tip-1 and ARHGEF16 may cooperate to activate Cdc42 and support a potential link between the expression of HPV16 E6 and Cdc42 activation | 21139582 |
| 2010-10-14 09:04:00 | The ephexin4 protein mediates cell migration through a RhoG-dependent mechanism. | 20679435 |
| Type | IDs |
|---|---|
| Synonymous | GEF16, NBR |
| Gene |
UniProtKB-ID:
ARHGG_HUMAN,
B3KTS4_HUMAN
UniprotKB:
Q5VV41,
B3KTS4
UniParc:
UPI00002039A3,
UPI000013CDAD,
UPI00003E5F06
EMBL:
BC051838,
BC002681,
AK095984,
BT007270,
D89016,
AL512413
Ensembl:
ENSG00000130762
KO:
hsa:27237
|
| Nucleutide sequences |
EMBL-CDS:
BAA13745.1,
AAH51838.1,
AAP35934.1,
AAH02681.1,
BAG53186.1
Ensembl_TRS:
ENST00000378373,
ENST00000378371,
ENST00000378378
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000367622,
ENSP00000367629,
ENSP00000367624
RefSeq:
XP_024302222.1,
NP_055263.2,
XP_016856539.1,
XP_016856538.1,
XP_016856540.1,
XP_024302223.1
|
| Others |
UniRef100:
UniRef100_B3KTS4,
UniRef100_Q5VV41
UniRef90:
UniRef90_Q5VV41
UniRef50:
UniRef50_Q5VV41
UniGene:
Hs.87435
CCDS:
CCDS46.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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