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27226 Pla2g7

27226

Pla2g7

phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)

protein-coding

Mus musculus

基因描述

Type Description
Definition phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)

研究结论

Date Results Publications
2020-07-11 10:04:00 PLA2G7 silencing can improve the myocardial fibrosis in mice with coronary atherosclerosis, and PLA2G7 is expected to be a potential target for coronary atherosclerosis 31053299
2018-07-07 12:09:00 Resveratrol downregulates Lp-PLA2 expression by inhibiting oxidative stress via SIRT1 pathway in a mouse model of chronic inflammation. 28608449
2015-12-05 10:26:00 Lp-PLA2 augments the inflammatory response after MI and antagonizes healing by disrupting the balance between inflammation and repair. 26232205
2015-07-04 12:17:00 Plg from mouse plasma contains oxPtdPC adducts that are not affected by the action of Lp-PLA(2), suggesting that linkage to Plg protects oxPtdPCs from metabolism during their transport in the plasma. 21614211
2013-10-26 10:59:00 SAA up-regulates Lp-PLA2 production significantly via a FPRL1/MAPKs./PPAR-gamma signaling pathway. 23623642

名称对应

Type IDs
Synonymous PAF-AH, R75400
Gene
UniProtKB-ID: PAFA_MOUSE
UniprotKB: Q60963
UniParc: UPI00000EB568
EMBL: CH466559, CT010585, AK051454, U34277, BC010726
Ensembl: ENSMUSG00000023913
KO: mmu:27226
Nucleutide sequences
EMBL-CDS: AAH10726.1, BAC34647.1, EDL23404.1, AAC52274.1, EDL23406.1
Ensembl_TRS: ENSMUST00000024706
Protein sequencees
Ensembl_PRO: ENSMUSP00000024706
RefSeq: XP_006524428.1, NP_038765.2, XP_006524429.1, XP_006524430.1
Others
UniRef100: UniRef100_Q60963
UniRef90: UniRef90_Q60963
UniRef50: UniRef50_Q13093
UniGene: Mm.9277
CCDS: CCDS28796.1

全选

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研究热度

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