| Type | Description |
|---|---|
| Definition | CART prepropeptide |
| Date | Results | Publications |
|---|---|---|
| 2020-05-30 10:21:00 | Expression of TSHR and of CART is suppressed in response to lipopolysaccharides within the arcuate nucleus in the hypothalamus of the mouse. The present findings highlight hypothalamic TSH receptor mechanisms and CART as putative adaptive neuroendocrine components in the response to acute inflammation. Findings suggest that central and peripheral CART is affected by acute inflammation. | 31829131 |
| 2018-11-10 11:21:00 | The potential mechanism of CART was determined to be associated with inflammatory cytokines and related apoptotic genes. CART therefore appears to be associated with DA in its effect on ischemic stroke and is protective against brain injury following ischemic stroke by reducing inflammation activation | 30066844 |
| 2017-10-28 10:57:00 | Study showed that the perikarya and central terminals of vagal afferents are invariably enriched in CART and devoid of melanin-concentrating hormone and that neuropeptidergic profile of the CART-positive vagal afferents is remarkably stable across the energy balance spectrum. | 27822503 |
| 2017-09-02 12:02:00 | Study conclude that CART is a regulator of glucose homeostasis and could play an important role in the pathophysiology of type 2 diabetes. Based on the ability of CART to increase insulin secretion and reduce glucagon secretion, CART-based agents could be a therapeutic modality in type 2 diabetes. | 27338624 |
| 2017-02-18 11:39:00 | Taken together, these results demonstrate that CART is a critical regulator of energy expenditure, energy partitioning and utilization dependent on the thermal environment. | 27080622 |
| Type | IDs |
|---|---|
| Synonymous | Cart |
| Gene |
UniProtKB-ID:
CART_MOUSE,
Q3UYI4_MOUSE
UniprotKB:
P56388,
Q3UYI4
UniParc:
UPI0000021C8A,
UPI000002A575
EMBL:
AF148071,
AK134656,
BC056431
Ensembl:
ENSMUSG00000021647
KO:
mmu:27220
|
| Nucleutide sequences |
EMBL-CDS:
AAF24168.1,
AAH56431.1,
BAE22228.1
Ensembl_TRS:
ENSMUST00000224142,
ENSMUST00000022150
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000022150,
ENSMUSP00000152981
RefSeq:
NP_038760.3,
NP_001074962.1
|
| Others |
UniRef100:
UniRef100_Q3UYI4,
UniRef100_P56388
UniRef90:
UniRef90_Q16568
UniRef50:
UniRef50_Q16568
UniGene:
Mm.75498
CCDS:
CCDS88509.1,
CCDS36763.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员