| Type | Description |
|---|---|
| Definition | G protein-coupled receptor 78 |
| Date | Results | Publications |
|---|---|---|
| 2019-12-21 11:26:00 | rs7676745, located near GPR78, associates with lower odds of surviving to the 90th percentile age. [Meta-analysis] | 31413261 |
| 2017-06-24 12:24:00 | We reveal distinct binding affinities between the binary and ternary complexes thus formed, that suggest a preference for the PERK signaling branch under stress, and a predilection for the GRP78-UPR sensor complex formation upon stressor removal. These results imply a gated UPR mechanism that tunes the overall cellular behavior to the accumulation of unfolded proteins. | 28416388 |
| 2017-01-28 11:21:00 | Knockdown of GPR78 in lung cancer cells suppressed cell migration and GPR78 modulated the formation of actin stress fibers in A549 cells, in a RhoA- and Rac1-dependent manner. | 27697106 |
| 2010-01-21 00:00:00 | Two haplotypes remained significant in both the female bipolar affective disorder individuals and in the full sample of affected female individuals. Results provide preliminary evidence for involvement of GPR78 in susceptibility to and SCZ. | 16389273 |
| 2009-04-08 21:32:00 | Observational study of gene-disease association. (HuGE Navigator) | 19328558 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
GPR78_HUMAN,
B2R7M4_HUMAN
UniprotKB:
Q96P69,
B2R7M4
UniParc:
UPI0000037A5F
EMBL:
AK313038,
AK128807,
JF810885,
BC057778,
AF411107,
AY359107,
BC069813,
AB065673,
BC069343,
CH471131
Ensembl:
ENSG00000155269
KO:
hsa:27201
|
| Nucleutide sequences |
EMBL-CDS:
AAH57778.1,
AAQ89465.1,
AAH69343.1,
BAC05898.1,
AAL26479.1,
AAH69813.1,
BAG35871.1,
BAG54739.1,
AEP43752.1,
EAW82336.1
Gene_ORFName:
UNQ5925/PRO19818,
hCG_17389
Ensembl_TRS:
ENST00000382487
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000371927
RefSeq:
NP_543009.2
|
| Others |
UniRef100:
UniRef100_Q96P69
UniRef90:
UniRef90_Q96P69
UniRef50:
UniRef50_Q96P69
UniGene:
Hs.740355
CCDS:
CCDS3403.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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