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27180 SIGLEC9

27180

SIGLEC9

sialic acid binding Ig like lectin 9

protein-coding

Homo sapiens

基因描述

Type Description
Definition sialic acid binding Ig like lectin 9

研究结论

Date Results Publications
2021-02-06 13:58:00 The Roles of Siglec7 and Siglec9 on Natural Killer Cells in Virus Infection and Tumour Progression. 32322597
2020-09-12 16:05:00 Targeting glycosylated antigens on cancer cells using siglec-7/9-based CAR T-cells. 32391973
2020-07-25 13:03:00 Expression of cognate Siglec-9 ligands was observed on the majority of tumor cells in primary and metastatic melanoma specimens. Targeting the tumor-restricted, glycosylation-dependent Siglec-9 axis may unleash this intratumoral T-cell subset, while confining T-cell activation to the tumor microenvironment. 30988027
2020-07-25 10:36:00 SS erythrocytes are deficient in binding to neutrophil Siglec-9 which may contribute to the increased oxidative stress in SCD. 31901888
2019-09-14 10:21:00 Targeting of the sialoglycan-SAMP/Siglec pathway in vitro and in vivo resulted in increased anticancer immunity. T cell expression of Siglec-9 in NSCLC patients correlated with reduced survival, and Siglec-9 polymorphisms showed association with the risk of developing lung and colorectal cancer. 30130255

名称对应

Type IDs
Synonymous CD329, CDw329, FOAP-9, OBBP-LIKE, siglec-9
Gene
UniProtKB-ID: SIGL9_HUMAN
UniprotKB: Q9Y336
UniParc: UPI00017A75A8, UPI00000389EE
EMBL: AY358913, AF135027, AF247180, AF227924, AB026265, AC011473, AK297043, BC035365
Ensembl: ENSG00000129450
KO: hsa:27180
Nucleutide sequences
EMBL-CDS: BAB41100.1, AAD26428.2, AAQ89272.1, AAF87223.1, AAH35365.2, AAG23261.1, BAG59570.1, AAF71455.1
Gene_ORFName: UNQ668/PRO1302
Ensembl_TRS: ENST00000440804, ENST00000250360
Protein sequencees
Ensembl_PRO: ENSP00000250360, ENSP00000413861
RefSeq: XP_011525034.1, XP_016882085.1, NP_055256.1, XP_016882084.1, NP_001185487.1, XP_011525032.1, XP_006723209.1
Others
UniRef100: UniRef100_Q9Y336
UniRef90: UniRef90_Q9Y336
UniRef50: UniRef50_Q96PQ1-2
UniGene: Hs.245828
CCDS: CCDS12825.1, CCDS56100.1

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