| Type | Description |
|---|---|
| Definition | glutaminase 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:31:00 | Nuclear Translocation of Glutaminase GLS2 in Human Associates with Proliferation Arrest and Differentiation. | 32042057 |
| 2020-09-19 16:31:00 | Liver-Type Glutaminase GLS2 Is a Druggable Metabolic Node in Luminal-Subtype Breast Cancer. | 31577957 |
| 2020-06-20 12:02:00 | Study verified that several breast cancer cell lines express endogenous GLS2 and GLS2 expression is linked to enhanced in vitro cell migration and invasion, mesenchymal markers and in vivo lung metastasis. GLS2 amplification or overexpression is linked to worse survival prognosis in breast cancer. Data establish an unforeseen role of GLS2 in sustaining tumor proliferation and underlying metastasis in breast cancer. | 31541193 |
| 2019-02-16 10:19:00 | Gene-based analysis of the 342 genes in the replication sample using SKAT-O identified one gene, GLS2, significantly associated with complicated Staphylococcus aureus bacteremia(p = 1.2 x 10-4) after Bonferroni correction. The strongest association across all 10,931 variants in the replication sample was with rs2657878 in GLS2 (p = 5 x 10-4). This variant is strongly correlated with a missense variant (rs2657879) | 30289878 |
| 2017-09-09 11:12:00 | This study assessed the relation of GLS2 downregulation in glioblastoma cells to its methylation and TP53 status. Aberrant methylation of CpG islands, appear to contribute to silencing of GLS2 in glioblastoma cells by a mechanism bypassing TP53 mutations. | 26258493 |
| Type | IDs |
|---|---|
| Synonymous | GA, GLS, LGA, hLGA |
| Gene |
UniProtKB-ID:
GLSL_HUMAN,
A0A087X004_HUMAN
UniprotKB:
Q9UI32,
A0A087X004
UniParc:
UPI0000E59764,
UPI0000061E10,
UPI00019151D3
EMBL:
AK303772,
AF348119,
AF110331,
AF223944,
CH471054,
AF110330,
AC097104
Ensembl:
ENSG00000135423
KO:
hsa:27165
|
| Nucleutide sequences |
EMBL-CDS:
AAO13298.2,
EAW96943.1,
AAF33826.1,
AAF21934.1,
BAH14045.1,
AAF21933.1,
EAW96945.1
Gene_ORFName:
hCG_24976
Ensembl_TRS:
ENST00000311966,
ENST00000486896,
ENST00000623608,
ENST00000610413
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000310447,
ENSP00000419661,
ENSP00000485315,
ENSP00000483010
RefSeq:
NP_037399.2,
NP_001267727.1,
NP_001267725.1,
XP_016874669.1,
XP_005268854.1,
NP_001267726.1
|
| Others |
UniRef100:
UniRef100_Q9UI32
UniRef90:
UniRef90_Q9UI32
UniRef50:
UniRef50_Q9UI32
UniGene:
Hs.212606
CCDS:
CCDS8921.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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