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271424 Ip6k3

271424

Ip6k3

inositol hexaphosphate kinase 3

protein-coding

Mus musculus

基因描述

Type Description
Definition inositol hexaphosphate kinase 3

研究结论

Date Results Publications
2018-06-09 10:46:00 High levels of IP6K3 mRNA were found in myotubes and muscle tissues. Expression was elevated under diabetic, fasting, and disuse conditions in mouse skeletal muscles. Ip6k3(-/-) mice had lower blood glucose, less insulin, decreased fat, lower weight, increased plasma lactate, enhanced glucose tolerance, lower glucose during an insulin tolerance test, and reduced muscle Pdk4 expression. Ip6k3 deletion extended lifespan. 27577108
2015-11-07 10:27:00 IP6K3 is highly expressed in cerebellar Purkinje cells. IP6K3-deleted mice display defects of motor learning and coordination. IP6K3-null mice manifest aberrations of Purkinje cells with a diminished number of synapses. 26245967

名称对应

Type IDs
Synonymous D830007E07Rik, Ihpk3
Gene
UniProtKB-ID: IP6K3_MOUSE
UniprotKB: Q8BWD2
UniParc: UPI00000222A4
EMBL: AK052857
Ensembl: ENSMUSG00000024210
KO: mmu:271424
Nucleutide sequences
EMBL-CDS: BAC35176.1
Ensembl_TRS: ENSMUST00000025046
Protein sequencees
Ensembl_PRO: ENSMUSP00000025046
RefSeq: NP_766615.1
Others
UniRef100: UniRef100_Q8BWD2
UniRef90: UniRef90_Q8BWD2
UniRef50: UniRef50_Q8BWD2
UniGene: Mm.209679
CCDS: CCDS28562.1

全选

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研究热度

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