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27133 KCNH5

27133

KCNH5

potassium voltage-gated channel subfamily H member 5

protein-coding

Homo sapiens

基因描述

Type Description
Definition potassium voltage-gated channel subfamily H member 5

研究结论

Date Results Publications
2020-12-26 13:13:00 Chloride intracellular channel 1 cooperates with potassium channel EAG2 to promote medulloblastoma growth. 32097463
2015-11-21 11:59:00 EAG2 potassium channel has an evolutionarily conserved function for promoting brain tumor growth. 26258683
2015-09-26 21:51:00 The observed Ca(2+)-induced proteolytic cleavage of EAG2 channel may act as an adaptive response under physiological and/or pathological conditions. 25542181
2015-01-10 13:32:00 Study propose that hypomethylation of the placental-specific KCNH5 promoter is frequently associated with KCNH5 expression in melanoma cells. 24759919
2013-12-14 12:34:00 Our results demonstrate the critical role of the Arg327 residue in stabilizing the channel closed state and explicate for the first time the structural and functional change of a Kv10.2 channel mutation associated with neurological disease. 24133262

名称对应

Type IDs
Synonymous EAG2, H-EAG2, Kv10.2, hEAG2
Gene
UniProtKB-ID: KCNH5_HUMAN
UniprotKB: Q8NCM2
UniParc: UPI0000039E2D, UPI000002ACA8, UPI000002ACA9
EMBL: AF418206, AK074484, BC073979, AL355101, AF493798, AF472412, AL132666, AL137191, AL109985, CH471061
Ensembl: ENSG00000140015
KO: hsa:27133
Nucleutide sequences
EMBL-CDS: BAC11016.1, AAM49574.1, AAM49565.1, EAW80819.1, AAM28435.1, AAH73979.1
Ensembl_TRS: ENST00000420622, ENST00000322893, ENST00000394968
Protein sequencees
Ensembl_PRO: ENSP00000378419, ENSP00000395439, ENSP00000321427
RefSeq: NP_758963.1, NP_647479.2
Others
UniRef100: UniRef100_Q8NCM2
UniRef90: UniRef90_Q8NCM2
UniRef50: UniRef50_Q8NCM2
UniGene: Hs.27043
CCDS: CCDS9756.1, CCDS45122.1

全选

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