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27131 SNX5

27131

SNX5

sorting nexin 5

protein-coding

Homo sapiens

基因描述

Type Description
Definition sorting nexin 5

研究结论

Date Results Publications
2021-02-27 13:51:00 Sorting nexin 5 mediates virus-induced autophagy and immunity. 33328639
2020-11-28 13:13:00 Upregulation of SNX5 predicts poor prognosis and promotes hepatocellular carcinoma progression by modulating the EGFR-ERK1/2 signaling pathway. 31819169
2020-09-05 13:57:00 SNX5 inhibits RLR-mediated antiviral signaling by targeting RIG-I-VISA signalosome. 31806368
2019-11-30 10:57:00 The studies identify a sorting motif and provide molecular insight into an evolutionary conserved coat complex, the 'Endosomal SNX-BAR sorting complex for promoting exit 1' (ESCPE-1), which couples sorting motif recognition to the BAR-domain-mediated biogenesis of cargo-enriched tubulo-vesicular transport carriers. 31576058
2019-04-20 10:57:00 Results indicate that SNX5 constitutive phosphorylation that mimics the mutant S226E decreases the active SNX5 in these cells. The phosphorylation of SNX5 regulates the dimerization with SNX1 or SNX2, and this suggests that it controls membrane trafficking and protein sorting. 30419003

名称对应

Type IDs
Gene
UniProtKB-ID: SNX5_HUMAN, Q6P5V6_HUMAN
UniprotKB: Q9Y5X3, Q6P5V6
UniParc: UPI00000703FC, UPI0000223FF9, UPI0000135B43
EMBL: BC093980, BC093623, AF121855, BC143274, BC000100, CH471133, AK001793, AK123903, BC062638, AL121585, BT007191
Ensembl: ENSG00000089006
KO: hsa:27131
Nucleutide sequences
EMBL-CDS: EAX10266.1, AAD27828.1, EAX10264.1, EAX10268.1, BAG53980.1, AAH93980.1, AAH93623.1, AAI43275.1, EAX10265.1, BAA91914.1, AAP35855.1, AAH62638.1
Ensembl_TRS: ENST00000606557, ENST00000377759, ENST00000377768
Protein sequencees
Ensembl_PRO: ENSP00000366988, ENSP00000366998, ENSP00000475510
RefSeq: NP_689413.1, NP_001269383.1, NP_055241.1
Others
UniRef100: UniRef100_Q9Y5X3, UniRef100_A0A2R8ZL06
UniRef90: UniRef90_Q9Y5X3
UniRef50: UniRef50_Q9Y5X3
UniGene: Hs.316890
CCDS: CCDS13130.1

全选

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