| Type | Description |
|---|---|
| Definition | AF4/FMR2 family member 4 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:18:00 | AFF4 enhances odontogenic differentiation of human dental pulp cells. | 32139123 |
| 2020-09-19 16:27:00 | AFF4 regulates osteogenic differentiation of human dental follicle cells. | 32606293 |
| 2020-06-13 10:47:00 | Clinical and molecular spectrum of CHOPS syndrome due to AFF4 mutations has been reported. | 31058441 |
| 2020-03-14 12:44:00 | The structure of the conserved AFF protein provides C-terminal homology domain and the molecular basis for the homo- and heterodimerization of AFF proteins. In addition, our data implicate the AFF4-CHD in nucleic acid interactions and identified a conserved loop region as a phosphorylation site for P-TEFb. | 31147444 |
| 2019-10-26 12:26:00 | AFF4 is functionally important target gene of METTL3 in bladder cancer. | 30659266 |
| Type | IDs |
|---|---|
| Synonymous | AF5Q31, CHOPS, MCEF |
| Gene |
UniProtKB-ID:
AFF4_HUMAN
UniprotKB:
Q9UHB7
UniParc:
UPI000066DA10,
UPI00000373C9,
UPI000006F558
EMBL:
CH471062,
AF161355,
BC137226,
AC004500,
AF197927,
BC063007,
BC100287,
AB209547,
AF213987
Ensembl:
ENSG00000072364
KO:
hsa:27125
|
| Nucleutide sequences |
EMBL-CDS:
AAH63007.1,
AAF18981.1,
BAD92784.1,
AAM00184.2,
AAF28915.1,
EAW62305.1,
AAI00288.1,
AAI37227.1
Gene_ORFName:
HSPC092
Ensembl_TRS:
ENST00000378595,
ENST00000265343
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000265343,
ENSP00000367858
RefSeq:
XP_005272021.1,
NP_055238.1,
XP_005272020.1,
XP_006714650.1
|
| Others |
UniRef100:
UniRef100_Q9UHB7
UniRef90:
UniRef90_Q9UHB7
UniRef50:
UniRef50_Q9UHB7
UniGene:
Hs.519313,
Hs.664840
CCDS:
CCDS4164.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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