| Type | Description |
|---|---|
| Definition | dickkopf WNT signaling pathway inhibitor 4 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-18 10:44:00 | The data implied that DLX3 regulated Wnt/beta-catenin pathway through histone modification of DKK4 during the osteogenic differentiation of bone marrow mesenchymal stem cells. | 31202458 |
| 2019-02-23 11:10:00 | Dkk4 CRD2 mediates high-affinity binding to both the E1E2 region of low-density lipoprotein receptor-related protein 6 (LRP6 E1E2) and the Kremen1 (Krm1) extracellular domain. | 29925589 |
| 2018-06-16 11:55:00 | Data suggest a critical role of dickkopf 4 (DKK4) in docetaxel resistance of the lung adenocarcinoma A549 (A549/DTX) cells. | 28981599 |
| 2018-04-28 10:19:00 | in NOD/SCID mice supplemented with high glucose, HepG2 xenografted tumors grew rapidly in which elevated levels of beta-catenin, c-Myc and decreased levels of DKK4 were detected. Knockdown of DKK4 by shRNA promotes proliferation of HCC cells in NG, which is suppressed by treating cells exogenously with recombinant DKK4 protein. Our in vitro and in vivo results indicate an important functional role of DKK4 in glucose fa... | 27272409 |
| 2018-03-31 11:46:00 | Our results indicated that DKK4 might be contributed to predicting EOC progression and prognosis. DKK4 could promote the invasion of EOC through JNK activation. | 28666421 |
| Type | IDs |
|---|---|
| Synonymous | DKK-4 |
| Gene |
UniProtKB-ID:
DKK4_HUMAN
UniprotKB:
Q9UBT3
UniParc:
UPI0000051057
EMBL:
BC107046,
AF177397,
BC107047,
AB017788,
AB018005
Ensembl:
ENSG00000104371
KO:
hsa:27121
|
| Nucleutide sequences |
EMBL-CDS:
AAF02677.1,
AAI07048.1,
BAA33438.1,
BAA33475.1,
AAI07047.1
Ensembl_TRS:
ENST00000220812
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000220812
RefSeq:
XP_011542790.1,
NP_055235.1,
XP_016868805.1
|
| Others |
UniRef100:
UniRef100_Q9UBT3
UniRef90:
UniRef90_Q9UBT3
UniRef50:
UniRef50_Q9UBT3
UniGene:
Hs.159311
CCDS:
CCDS6130.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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