| Type | Description |
|---|---|
| Definition | MDM2 binding protein |
| Date | Results | Publications |
|---|---|---|
| 2016-02-20 11:53:00 | data show that MTBP aggravates the invasion and metastasis of HCC by promoting the MDM2-mediated degradation of E-cadherin. | 26280083 |
| 2015-06-20 12:09:00 | Overexpression of MTBP resulted in the suppression of the migratory and metastatic potential of Hepatocellular carcinoma cells, while its downregulation increased the migration. | 25759210 |
| 2015-06-06 10:15:00 | MTBP significantly contributes to breast cancer survival and is a potential novel therapeutic target in Triple-negative breast cancer . | 24866769 |
| 2014-10-18 12:07:00 | MTBP associated with MYC at promoters and increased MYC-mediated transcription, proliferation, neoplastic transformation, and tumor development. | 24786788 |
| 2013-06-15 11:36:00 | MTBP acts with Treslin/TICRR to integrate signals from cell cycle and DNA damage response pathways to control the initiation of DNA replication in human cells. | 23704573 |
| Type | IDs |
|---|---|
| Synonymous | MDM2BP |
| Gene |
UniProtKB-ID:
MTBP_HUMAN
UniprotKB:
Q96DY7
UniParc:
UPI00000703F0,
UPI00017A7F95
EMBL:
AC105142,
CH471060,
BC013136,
AK300762,
AC107877,
AK022122
Ensembl:
ENSG00000172167
KO:
hsa:27085
|
| Nucleutide sequences |
EMBL-CDS:
EAW92007.1,
AAH13136.1,
BAG62427.1,
BAB13965.1,
EAW92006.1
Ensembl_TRS:
ENST00000523373,
ENST00000305949
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000430771,
ENSP00000303398
RefSeq:
NP_071328.2,
XP_011515264.1,
XP_011515265.1
|
| Others |
UniRef100:
UniRef100_Q96DY7
UniRef90:
UniRef90_Q96DY7
UniRef50:
UniRef50_Q96DY7
UniGene:
Hs.657656
CCDS:
CCDS6333.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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