| Type | Description |
|---|---|
| Definition | nitrilase 1 |
| Date | Results | Publications |
|---|---|---|
| 2017-12-09 11:40:00 | Data show that cisplatin response was enhanced in human lung cancer cells when Nit1 was knocked down and mice Nit1-/-:KrasG12D/+ tumors showed increased sensitivity to cisplatin in vivo. | 26967383 |
| 2010-01-21 00:00:00 | the extent of tumor susceptibility due to Nit1 and Fhit deficiency is additive | 19479888 |
| 2010-01-21 00:00:00 | Nit1 and Fhit share tumor suppressor signaling pathways, while localization of the NIT1 gene at a stable chromosome site explains the paucity of gene alterations and in frequent loss of expression of the NIT1 gene in human malignancies. | 16864578 |
| 2010-01-21 00:00:00 | genetic deficiency results in T cell hyperproliferative responses induced by TCR stimulation, spontaneous cell cycle entry and enhanced cell cycle progression | 19395373 |
| Type | IDs |
|---|---|
| Synonymous | AI255805, ESTM30, W57327 |
| Gene |
UniProtKB-ID:
NIT1_MOUSE
UniprotKB:
Q8VDK1
UniParc:
UPI00001EDEF7,
UPI00000294BA
EMBL:
AF069985,
BC021634,
AF069988
Ensembl:
ENSMUSG00000013997
KO:
mmu:27045
|
| Nucleutide sequences |
EMBL-CDS:
AAH21634.1,
AAC40185.1,
AAC40184.1
Ensembl_TRS:
ENSMUST00000111289,
ENSMUST00000111295
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000106926,
ENSMUSP00000106920
RefSeq:
XP_006496929.1,
NP_001229509.1,
NP_036179.1
|
| Others |
UniRef100:
UniRef100_Q8VDK1
UniRef90:
UniRef90_Q8VDK1
UniRef50:
UniRef50_Q8VDK1
UniGene:
Mm.12915,
Mm.270139
CCDS:
CCDS35775.1,
CCDS56656.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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