| Type | Description |
|---|---|
| Definition | GTPase activating protein (SH3 domain) binding protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-02-29 11:30:00 | Replacement of endogenous G3BP1 with the K376Q mutant or the RNA binding-deficient F380L/F382L mutant interfered with SG formation. Significant G3BP1 K376 acetylation was detected during SG resolution, and K376-acetylated G3BP1 was seen outside SGs. G3BP1 acetylation is regulated by histone deacetylase 6 (HDAC6) and CBP/p300. | 31481451 |
| 2020-02-15 13:09:00 | By combining three complimentary approaches, the authors identify the host protein G3BP1 as a critical host factor required for norovirus VPg-dependent translation, identifying a new role for G3BP1 in virus-specific translation. | 31403400 |
| 2020-02-15 10:39:00 | We show that murine norovirus (MNV) further prevents the formation of cytoplasmic stress granules, by recruiting the key host protein G3BP1 to the MNV replication complex, a recruitment that is crucial to establishing and maintaining virus replication. | 31213553 |
| 2019-05-25 12:20:00 | this paper shows that G3BP1 promotes DNA binding and activation of cyclic GMP-AMP synthase | 30510222 |
| 2017-09-23 11:06:00 | the aberrant mutant SOD1-G3BP1 interaction affects stress granule dynamics | 27481264 |
| Type | IDs |
|---|---|
| Synonymous | AI849976, B430204O07, C87777, G3bp, mKIAA4115 |
| Gene |
UniProtKB-ID:
G3BP1_MOUSE
UniprotKB:
P97855
UniParc:
UPI000000199F
EMBL:
AB001927,
BC021156
Ensembl:
ENSMUSG00000018583
KO:
mmu:27041
|
| Nucleutide sequences |
EMBL-CDS:
BAA19469.1,
AAH21156.1
Ensembl_TRS:
ENSMUST00000018727
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000018727
RefSeq:
XP_030101903.1,
XP_030101902.1,
NP_038744.1
|
| Others |
UniRef100:
UniRef100_P97855
UniRef90:
UniRef90_P97855
UniRef50:
UniRef50_Q13283
UniGene:
Mm.39631,
Mm.380129,
Mm.405739
CCDS:
CCDS24714.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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