| Type | Description |
|---|---|
| Definition | linker for activation of T cells |
| Date | Results | Publications |
|---|---|---|
| 2020-10-03 12:59:00 | LRCH1 deficiency enhances LAT signalosome formation and CD8(+) T cell responses against tumors and pathogens. | 32727906 |
| 2019-07-13 11:24:00 | that LAT1 is not only associated with poor prognosis of ovarian carcinoma, but also associated with chemoresistance in ovarian carcinoma | 30637450 |
| 2019-06-22 11:51:00 | LAT, once internalized, transits through the Golgi-trans-Golgi network (TGN), where it is repolarized to the immune synapse. | 29440364 |
| 2019-04-20 11:36:00 | Discovery of a conserved proline-rich motif in LAT that mediates efficient LAT phosphorylation. | 29915297 |
| 2018-12-22 11:46:00 | Plasma membrane LAT activation precedes vesicular recruitment defining two phases of early T-cell activation. | 29789604 |
| Type | IDs |
|---|---|
| Synonymous | IMD52, LAT1, pp36 |
| Gene |
UniProtKB-ID:
LAT_HUMAN,
A0A024QZD6_HUMAN
UniprotKB:
O43561,
A0A024QZD6
UniParc:
UPI00005A7621,
UPI0001B07FAF,
UPI0000000CB2,
UPI00001FFDB1,
UPI000012E238
EMBL:
FN432832,
AC109460,
AF036906,
AJ223280,
AF036905,
BC011563,
CH471267
Ensembl:
ENSG00000213658
KO:
hsa:27040
|
| Nucleutide sequences |
EMBL-CDS:
AAC39636.1,
EAW52027.1,
CAA11218.1,
CBA11533.1,
AAH11563.1,
EAW52028.1,
AAC39637.1,
EAW52030.1,
EAW52029.1
Gene_ORFName:
hCG_2039637
Ensembl_TRS:
ENST00000564277,
ENST00000395461,
ENST00000566177,
ENST00000360872,
ENST00000454369,
ENST00000395456
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000398793,
ENSP00000378845,
ENSP00000456761,
ENSP00000354119,
ENSP00000378841,
ENSP00000457036
RefSeq:
NP_001014988.1,
NP_001014987.1,
NP_055202.1,
NP_001014989.2
|
| Others |
UniRef100:
UniRef100_O43561
UniRef90:
UniRef90_O43561
UniRef50:
UniRef50_O43561
UniGene:
Hs.632179
CCDS:
CCDS32425.1,
CCDS45455.1,
CCDS53999.1,
CCDS10647.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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