| Type | Description |
|---|---|
| Definition | tRNA methyltransferase 2 homolog A |
| Date | Results | Publications |
|---|---|---|
| 2019-12-07 10:38:00 | Our associated finding of extensive irreversible TRMT2A-tRNA crosslinking in vivo following 5-Fluorouracil exposure is also intriguing, as it suggests a tangible mechanism for a previously suspected RNA-dependent route of Fluorouracil-mediated cytotoxicity. | 31361898 |
| 2019-06-08 12:57:00 | tRNA methyltransferase 2 homolog A (TRMT2A) protein harbors an RNA recognition motif in the N-terminus and the conserved uracil-C5-methyltransferase domain of the TrmA family in the C-terminus. TRMT2A predominantly localizes to the nucleus in HeLa cells. TRMT2A-overexpressing cells display decreased cell proliferation and altered DNA content, while TRMT2A-deficient cells exhibit increased growth. | 30502085 |
| 2010-06-28 12:08:00 | TRMT2A staining showed a strong correlation with likelihood of recurrence at five years in 67 HER2+ breast cancer. | 20307320 |
| 2010-01-21 00:00:00 | Single nucleotid polymorphisms of this gene may be associated with a deficit in sustained attention within schizophrenia, in a Taiwanese cohort. | 18075473 |
| 2008-03-13 08:55:00 | Observational study of gene-disease association. (HuGE Navigator) | 18075473 |
| Type | IDs |
|---|---|
| Synonymous | HTF9C |
| Gene |
UniProtKB-ID:
TRM2A_HUMAN,
F2Z2W7_HUMAN
UniprotKB:
Q8IZ69,
F2Z2W7
UniParc:
UPI00001609D9,
UPI00001BBFC5,
UPI0000403164
EMBL:
AC006547,
BC108251,
CH471176,
AK025106,
AK057029,
CR456354,
BC013352,
BC017184
Ensembl:
ENSG00000099899
KO:
hsa:27037
|
| Nucleutide sequences |
EMBL-CDS:
EAX02997.1,
CAG30240.1,
BAB15067.1,
AAI08252.1,
AAH13352.2,
BAB71349.1,
EAX02996.1,
AAH17184.2
Ensembl_TRS:
ENST00000252136,
ENST00000404751,
ENST00000403707,
ENST00000439169
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000252136,
ENSP00000385807,
ENSP00000384968,
ENSP00000395738
RefSeq:
XP_011528441.1,
NP_001244923.1,
XP_011528444.1,
NP_001317968.1,
NP_073564.3,
XP_011528443.1,
NP_892029.2
|
| Others |
UniRef100:
UniRef100_Q8IZ69,
UniRef100_F2Z2W7
UniRef90:
UniRef90_Q8IZ69
UniRef50:
UniRef50_Q8IZ69
UniGene:
Hs.713579
CCDS:
CCDS13774.1,
CCDS58793.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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