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27020 NPTN

27020

NPTN

neuroplastin

protein-coding

Homo sapiens

基因描述

Type Description
Definition neuroplastin

研究结论

Date Results Publications
2020-05-23 12:52:00 Hippocampal expression of neuroplastin is altered in Alzheimer's disease. 30488668
2019-11-09 12:52:00 Expression profiling of NPTNbeta showed significantly high expression levels in lung cancer cell lines. NPTNbeta has strong ability to induce cancer-related cellular events, including anchorage-independent growth, motility and invasiveness, in lung cancer cells in response to extracellular S100A8/A9, eventually leading to the expression of a cancer disseminative phenotype in lung tissue in vivo. 30720226
2019-02-23 13:33:00 these results indicate that epilation induces McSCs activation through EDN3/EDNRB signaling and in turn leads to skin and hair hyperpigmentation. The findings suggest that EDN/EDNRB signaling may serve as a potential therapeutic target to promote repigmentation in hypopigmentation disorders. 28779130
2018-12-29 12:32:00 Cryoelectron microscopy structure offers important insight into how the NPTN binds to the PMCA1. 30190470
2018-01-27 11:32:00 Xkr8-BSG/NPTN complex is required for phosphatidylserine scrambling in apoptotic cell membranes. 27503893

名称对应

Type IDs
Synonymous GP55, GP65, SDFR1, SDR1, np55, np65
Gene
UniProtKB-ID: NPTN_HUMAN
UniprotKB: Q9Y639
UniParc: UPI00006688C8, UPI0000036A43, UPI0000072D5C, UPI000189287E, UPI00006688C9
EMBL: BC105979, CH471082, AK314248, AF109127, BC143880, BC117462, AK297184, BC143881, AF109126, AB209812
Ensembl: ENSG00000156642
KO: hsa:27020
Nucleutide sequences
EMBL-CDS: AAD43218.1, BAG36914.1, BAH12519.1, BAD93049.1, AAI43882.1, AAI17463.1, AAI05980.1, AAI43881.1, AAD43217.1, EAW77931.1
Ensembl_TRS: ENST00000351217, ENST00000562924, ENST00000563691, ENST00000345330
Protein sequencees
Ensembl_PRO: ENSP00000290401, ENSP00000456349, ENSP00000342958, ENSP00000457028
RefSeq: NP_001154836.1, XP_024305667.1, NP_036560.1, XP_011519754.1, XP_024305668.1, NP_059429.1, NP_001154835.1
Others
UniRef100: UniRef100_Q9Y639
UniRef90: UniRef90_Q9Y639
UniRef50: UniRef50_Q9Y639
UniGene: Hs.744867
CCDS: CCDS10250.1, CCDS10249.1, CCDS58379.1, CCDS58380.1

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