| Type | Description |
|---|---|
| Definition | gap junction protein alpha 5 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-13 13:27:00 | BIRC5, GAJ5, and lncRNA NPHP3-AS1 Are Correlated with the Development of Atrial Fibrillation-Valvular Heart Disease. | 33518654 |
| 2020-07-04 10:54:00 | KCNE2 rs8134775 was associated with a decreased atrial fibrillation (AF) risk in the Chinese Han population in the allele model. Minor allele T of GJA5 rs35594137 was associated with a decreased AF risk, and the minor allele G of KCNJ2 rs8079702 was associated with an increased AF risk in the recessive models. Results suggest that KCNE2, KCNJ2, and GJA5 influence the development of AF in the Chinese Han population. | 31270966 |
| 2020-01-11 11:53:00 | Cx40 or Cx45 Gap junctions showed little changes in the extent of voltage-dependent-gating, but in both cases with a faster deactivation kinetics at high temperatures. | 30594539 |
| 2019-07-20 12:40:00 | By 143 days gestational age, the developing heart has the classical helical organization observed in mature mammalian tissue. This was accompanied by an increase in connexin 43 and connexin 40 expression levels, suggesting their role in the development of the ventricular conduction system and that electrical propagation across the heart is facilitated in later gestation. | 28947768 |
| 2018-09-29 11:34:00 | Atrial Fibrillation (AF)-linked Cx40 mutants impair gap junction and/or hemichannel function, which may predispose the mutant carriers to AF. | 29587382 |
| Type | IDs |
|---|---|
| Synonymous | ATFB11, CX40 |
| Gene |
UniProtKB-ID:
CXA5_HUMAN,
X5D2H9_HUMAN
UniprotKB:
P36382,
X5D2H9
UniParc:
UPI000013D8D2
EMBL:
LT990257,
BT019416,
BC013313,
U03486,
AF151979,
L34954,
CH471223,
AL365260,
KJ534844,
BT019415
Ensembl:
ENSG00000265107
KO:
hsa:2702
|
| Nucleutide sequences |
EMBL-CDS:
AAH13313.1,
AAA60457.2,
AAA91833.1,
AAV38223.1,
AAV38222.1,
CAI14125.1,
CAI14124.1,
AAD37801.1,
EAW50930.1,
EAW50929.1,
VZP20057.1,
AHW56484.1
Gene_ORFName:
hCG_1770483
Ensembl_TRS:
ENST00000621517,
ENST00000579774
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000484552,
ENSP00000463851
RefSeq:
NP_859054.1,
XP_005273008.1,
NP_005257.2,
XP_016856533.1
|
| Others |
UniRef100:
UniRef100_P36382
UniRef90:
UniRef90_P36382
UniRef50:
UniRef50_P36382
UniGene:
Hs.447968
CCDS:
CCDS929.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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