| Type | Description |
|---|---|
| Definition | thiamin pyrophosphokinase 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:31:00 | TPK1 as a predictive marker for the anti-tumour effects of simvastatin in gastric cancer. | 31964553 |
| 2019-03-30 11:46:00 | any disease mutants are directly or indirectly involved in thiamine binding. Thus, our study provided a novel rationale for thiamine supplementation, so far the major therapeutic intervention in TPK deficiency. | 30483896 |
| 2014-03-08 12:05:00 | These findings demonstrate that the genes involved in dictating thiamine homeostasis, such as SLC19A2, SLC25A19 and TPK-1, were significantly up-regulated in clinical tissues and breast cancer cell lines. | 23642734 |
| 2012-02-04 11:33:00 | Mutation analysis of TPK1 uncovered three missense, one splice-site, and one frameshift mutation resulting in decreased TPK protein levels | 22152682 |
| 2010-06-30 22:05:00 | Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | 20379614 |
| Type | IDs |
|---|---|
| Synonymous | HTPK1, PP20, THMD5 |
| Gene |
UniProtKB-ID:
TPK1_HUMAN,
A0A090N8Y0_HUMAN,
F5GZG6_HUMAN
UniprotKB:
Q9H3S4,
A0A090N8Y0,
F5GZG6
UniParc:
UPI000004FD50,
UPI000056F1AD,
UPI00001AEE82
EMBL:
CH471146,
AF297710,
AC004534,
AC074384,
BC040555,
AC005677,
AC004833,
AC004743,
AK289652,
AY206415,
AACC02000041,
AK026374,
AC004864,
KF458633,
AB028138,
BC068460
Ensembl:
ENSG00000196511
KO:
hsa:27010
|
| Nucleutide sequences |
EMBL-CDS:
AAO38775.1,
EAW80092.1,
BAB15465.1,
BAB20326.1,
AAK01351.1,
AAH40555.1,
AAH68460.1,
BAF82341.1,
EAW80091.1,
EAL24415.1
Gene_ORFName:
tcag7.508
Ensembl_TRS:
ENST00000360057,
ENST00000378099
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000353165,
ENSP00000367339
RefSeq:
NP_001337823.1,
XP_016867469.1,
XP_016867464.1,
NP_001337816.1,
NP_001337814.1,
XP_011514350.1,
XP_011514336.1,
XP_011514337.1,
NP_001337818.1,
XP_011514333.1,
XP_011514339.1,
NP_001337812.1,
XP_011514341.1,
NP_071890.2,
XP_011514349.1,
XP_024302485.1,
XP_016867463.1,
NP_001337811.1,
XP_016867471.1,
NP_001337808.1,
XP_011514342.1,
XP_016867459.1,
NP_001337810.1,
XP_011514348.1,
NP_001337809.1,
XP_011514335.1,
NP_001337813.1,
NP_001337822.1,
NP_001337824.1,
XP_016867460.1,
XP_024302483.1,
XP_011514334.1,
NP_001035947.1,
NP_001337815.1,
XP_011514345.1,
XP_024302484.1,
XP_016867458.1,
XP_016867461.1,
XP_016867470.1,
XP_005250027.1
|
| Others |
UniRef100:
UniRef100_F5GZG6,
UniRef100_Q9H3S4
UniRef90:
UniRef90_Q9H3S4,
UniRef90_A0A2I3MND8
UniRef50:
UniRef50_Q9H3S4
UniGene:
Hs.660232
CCDS:
CCDS5888.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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