| Type | Description |
|---|---|
| Definition | gap junction protein alpha 4 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-18 12:18:00 | Our data demonstrate that Cx37 expression is differentially regulated by shear stress and SMAD1/5 signaling, and that reduced Cx37 expression is permissive for capillary enlargement into shunts. | 32078368 |
| 2020-06-27 11:56:00 | interaction with PDE4D gene polymorphisms and susceptibility to ischemic stroke in Chinese population | 31653176 |
| 2020-03-28 12:03:00 | Cx37 SNP rs1764391 may contribute to the risk for acute myocardial infarction (AMI), especially in women. This genetic variant may prove to be a potential biomarker for AMI risk stratification and may prove to be a useful target for therapeutic intervention to further improve prognosis in high-risk patients. | 31580250 |
| 2020-01-11 11:53:00 | Cx37/Cx43 and Cx37/Cx45 gap junctions (GJs), but not Cx37/Cx40 GJs, were functional and each with unique rectifying channel properties. | 30594540 |
| 2018-10-06 10:52:00 | Data show that fluid shear stress activates NOTCH signaling, which upregulates GJA4 (commonly, Cx37) and downstream cell cycle inhibitor CDKN1B (p27). | 29247167 |
| Type | IDs |
|---|---|
| Synonymous | CX37 |
| Gene |
UniProtKB-ID:
CXA4_HUMAN
UniprotKB:
P35212
UniParc:
UPI000013E8EF
EMBL:
AF139102,
CH471059,
M96789,
AK291563,
BC072389,
AF132674,
AF139104,
AF181620,
BC027889,
AF139101,
AF139105,
AF139103,
AF139100,
AL121988
Ensembl:
ENSG00000187513
KO:
hsa:2701
|
| Nucleutide sequences |
EMBL-CDS:
AAD31873.1,
AAA52558.2,
AAD31871.1,
AAD56940.1,
AAH72389.1,
AAD31874.1,
EAX07441.1,
AAD31872.1,
AAD31870.1,
AAF62342.1,
EAX07440.1,
AAD31869.1,
AAH27889.1,
BAF84252.1
Ensembl_TRS:
ENST00000342280
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000343676
RefSeq:
XP_016856532.1,
XP_005270807.1,
NP_002051.2
|
| Others |
UniRef100:
UniRef100_P35212
UniRef90:
UniRef90_P35212
UniRef50:
UniRef50_P35212
UniGene:
Hs.296310
CCDS:
CCDS30669.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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