| Type | Description |
|---|---|
| Definition | lysophosphatidylcholine acyltransferase 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-26 13:12:00 | Lysophosphatidylcholine acyltransferase 2 (LPCAT2) co-localises with TLR4 and regulates macrophage inflammatory gene expression in response to LPS. | 32587324 |
| 2018-01-13 13:52:00 | Selected compounds competed with acetyl-CoA for the inhibition of LPCAT2 lyso-PAFAT activity and suppressed PAF biosynthesis in mouse peritoneal macrophages stimulated with a calcium ionophore. These compounds had low inhibitory effects on LPCAT1 activity, indicating that adverse effects on respiratory functions may be avoided. | 24850807 |
| 2017-09-23 11:49:00 | LPCAT2 was detected in wild-type spinal cord microglia, and the absence of LPCAT2 expression precluded spinal platelet-activating factor expression in LPCAT2-knockout mice. | 28341636 |
| 2014-10-11 10:10:00 | We show a new signaling pathway for rapid biosynthesis of PAF that is mediated by phosphorylation of LPCAT2 at Ser-34. | 24742674 |
| 2010-10-23 10:04:00 | Specific inhibition of the PAF biosynthetic activity by phosphorylated LPCAT2 will provide a novel target for the regulation of inflammatory disorders. | 20663880 |
| Type | IDs |
|---|---|
| Synonymous | 1-AGPAT 11, A330042H22, Aytl1, Aytl1a, lpafat1, lysoPAFAT, lysoPAFAT/LPCAT2 |
| Gene |
UniProtKB-ID:
PCAT2_MOUSE
UniprotKB:
Q8BYI6
UniParc:
UPI00019B220E,
UPI0000027862,
UPI00019B220D
EMBL:
AK039431,
EF442784,
EF442783,
AB244716
Ensembl:
ENSMUSG00000033192
KO:
mmu:270084
|
| Nucleutide sequences |
EMBL-CDS:
ABR20913.1,
ABR20912.1,
BAF47695.1,
BAC30345.1
Ensembl_TRS:
ENSMUST00000209265,
ENSMUST00000046290,
ENSMUST00000210099
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000147941,
ENSMUSP00000148089,
ENSMUSP00000049252
RefSeq:
NP_001344303.1,
NP_766602.1,
NP_001344304.1
|
| Others |
UniRef100:
UniRef100_Q8BYI6
UniRef90:
UniRef90_Q8BYI6
UniRef50:
UniRef50_Q8BYI6
UniGene:
Mm.21463
CCDS:
CCDS22524.1,
CCDS90434.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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