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269966 Nup98

269966

Nup98

nucleoporin 98

protein-coding

Mus musculus

基因描述

Type Description
Definition nucleoporin 98

研究结论

Date Results Publications
2020-12-12 13:23:00 TLR2/6 signaling promotes the expansion of premalignant hematopoietic stem and progenitor cells in the NUP98-HOXD13 mouse model of MDS. 32652111
2020-04-11 12:41:00 RAE1 and NUP98 participate inBMAL1 shuttling and promote the degradation and activity of BMAL1 and CLOCK. 30683868
2019-11-02 10:28:00 NHD13 transgenic mice lacking Lyl1 showed accelerated T-ALL and absence of transformation to AML, associated with a loss of multipotent progenitors in the bone marrow. 30700838
2017-06-24 12:19:00 We demonstrated that Nup98-TopIIbeta and Nup98-SETBP1 negatively regulate the XPO1-mediated protein export. Our results will contribute to the understanding of the molecular mechanism by which the Nup98-fusion proteins induce tumorigenesis. 28392395
2015-12-26 10:05:00 The age-associated accumulation of somatic mutations that occurs in the Nup98-HOXD13 (NHD13) mouse model of leukemia progression was significantly elevated by co-expression of a PKR transgene. 26202421

名称对应

Type IDs
Synonymous 4732457F17, AI849286, Nup96
Gene
UniProtKB-ID: NUP98_MOUSE, B2RQL0_MOUSE, Q3UJE5_MOUSE, A0A1B0GRA7_MOUSE, A0A1B0GSX7_MOUSE, A0A140T8J8_MOUSE, Q4FZE7_MOUSE, A0A1B0GRB5_MOUSE, Q3TPG3_MOUSE
UniprotKB: Q6PFD9, B2RQL0, Q3UJE5, A0A1B0GRA7, A0A1B0GSX7, A0A140T8J8, Q4FZE7, A0A1B0GRB5, Q3TPG3
UniParc: UPI000056D29A, UPI0003C8501E, UPI0000563FCA, UPI0002B8CBF9, UPI00005B2077, UPI00001CDF42, UPI00005AC572, UPI0001F791A3, UPI00001F5C82
EMBL: BC099600, AK146491, AK164402, BC112912, BC078630, BC050911, AC118592, BC137975, BC057608
Ensembl: ENSMUSG00000063550
KO: mmu:269966
Nucleutide sequences
EMBL-CDS: AAH78630.1, AAH57608.1, AAI12913.1, AAH50911.1, AAI37976.1, BAE27210.1, AAH99600.1, BAE37773.1
Ensembl_TRS: ENSMUST00000211235, ENSMUST00000211005, ENSMUST00000210682, ENSMUST00000070165, ENSMUST00000211022
Protein sequencees
Ensembl_PRO: ENSMUSP00000147486, ENSMUSP00000147445, ENSMUSP00000148115, ENSMUSP00000068530, ENSMUSP00000147454
RefSeq: NP_001274093.1, XP_006507958.1, NP_001274094.1, NP_075355.1, XP_030098483.1, XP_006507960.1, XP_006507959.1, XP_030098484.1, NP_001274096.1, NP_001274095.1
Others
UniRef100: UniRef100_A0A1B0GRA7, UniRef100_A0A1B0GRB5, UniRef100_Q3TPG3, UniRef100_B7ZN81, UniRef100_A0A1B0GSX7, UniRef100_B2RQL0, UniRef100_Q6PFD9, UniRef100_Q3UJE5
UniRef90: UniRef90_P52948-3, UniRef90_P49793-2, UniRef90_Q6PFD9
UniRef50: UniRef50_P52948, UniRef50_P52948-3
UniGene: Mm.439800, Mm.486276
CCDS: CCDS85358.1

全选

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研究热度

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