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269951 Idh2

269951

Idh2

isocitrate dehydrogenase 2 (NADP+), mitochondrial

protein-coding

Mus musculus

基因描述

Type Description
Definition isocitrate dehydrogenase 2 (NADP+), mitochondrial

研究结论

Date Results Publications
2021-03-13 13:18:00 SUMOylation enhances the activity of IDH2 under oxidative stress. 32900482
2021-02-20 13:36:00 IDH2 Deficiency Is Critical in Myogenesis and Metabolism in Mice Skeletal Muscle. 32764267
2020-09-05 13:57:00 Reactive oxygen species-mediated senescence is accelerated by inhibiting Cdk2 in Idh2-deficient conditions. 31503005
2020-08-29 12:47:00 IDH2 deficiency increases bone mass with reduced osteoclastogenesis by limiting RANKL expression in osteoblasts. 31479775
2020-06-20 11:50:00 these results established IDH2 as a critical suppressor of steatohepatitis 31064654

名称对应

Type IDs
Synonymous E430004F23, IDPm, Idh-2
Gene
UniProtKB-ID: IDHP_MOUSE
UniprotKB: P54071
UniParc: UPI00000EA006
EMBL: AF212319, AK145753, AK169395, U51167, BC060030, AK088110, AK161640
Ensembl: ENSMUSG00000030541
KO: mmu:269951
Nucleutide sequences
EMBL-CDS: AAC52473.1, BAE26628.1, BAE41142.1, AAG43538.1, AAH60030.1, BAC40149.1, BAE36505.1
Ensembl_TRS: ENSMUST00000107384
Protein sequencees
Ensembl_PRO: ENSMUSP00000103007
RefSeq: XP_006540974.1, NP_766599.2
Others
UniRef100: UniRef100_P54071
UniRef90: UniRef90_P54071
UniRef50: UniRef50_P54071
UniGene: Mm.246432, Mm.290925
CCDS: CCDS39994.1

全选

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研究热度

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