| Type | Description |
|---|---|
| Definition | bromodomain containing 7 |
| Date | Results | Publications |
|---|---|---|
| 2018-10-27 10:41:00 | A novel basis for understanding the molecular dynamics of glucose metabolism and the unique function of BRD7 in the regulation of glucose homeostasis. | 29127434 |
| 2018-05-26 11:22:00 | these findings suggest that BRD7 has an anti-inflammatory role during early acute inflammation by inhibiting activation of the NF-small ka, CyrillicB signaling pathway, which provides evidence to aid in understanding the therapeutic effects of BRD7 on inflammatory diseases | 27374794 |
| 2018-02-17 11:19:00 | Furthermore, Brd7 inhibition alters the phenotype of macrophages and promotes plaque instability, at least partly via signaling. Our data define a previously undescribed role of Brd7 in the development of atherosclerosis. | 29273506 |
| 2017-07-08 11:53:00 | Homozygous BRD7 knockout (KO) mice showed retardation in development. | 27444544 |
| 2017-01-14 11:10:00 | Homozygous knockout of BRD7 (BRD7(-/-)) resulted in complete male infertility and spermatogenesis defects, including deformed acrosomal formation, degenerative elongating spermatids and irregular head morphology in postmeiotic germ cells in the seminiferous epithelium, which led to the complete arrest of spermatogenesis at step 13. | 26878912 |
| Type | IDs |
|---|---|
| Synonymous | BP75, CELTIX1, Ptpn13ip |
| Gene |
UniProtKB-ID:
BRD7_MOUSE
UniprotKB:
O88665
UniParc:
UPI0000029A40
EMBL:
AF084259,
AK004429,
AK138934,
AK142758
Ensembl:
ENSMUSG00000031660
KO:
mmu:26992
|
| Nucleutide sequences |
EMBL-CDS:
AAC33302.1,
BAE25187.1,
BAE23823.1,
BAB23299.1
Ensembl_TRS:
ENSMUST00000034085
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000034085
RefSeq:
NP_001363944.1,
NP_001363942.1,
NP_001363943.1,
NP_001363946.1,
NP_001363945.1,
NP_036177.1
|
| Others |
UniRef100:
UniRef100_O88665
UniRef90:
UniRef90_O88665
UniRef50:
UniRef50_O88665
UniGene:
Mm.5400
CCDS:
CCDS22510.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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