| Type | Description |
|---|---|
| Definition | multiple EGF-like-domains 8 |
| Date | Results | Publications |
|---|---|---|
| 2018-01-30 09:49:00 | Megf8 attenuates signaling through the Hedgehog pathway by reducing levels of Smoothened at the cell surface and the primary cilium. Mutations in Megf8 lead to cardiac defects, limb defects, left-right patterning defects and craniofacial anomalies. | 29290584 |
| 2015-05-16 12:23:00 | Megf8 is involved in mediating BMP4 signaling and guidance of developing trigeminal ganglia axons. | 24052814 |
| Type | IDs |
|---|---|
| Synonymous | AW049492, Egfl4, b2b1702.2Clo, b2b1702Clo, b2b288Clo, m687Ddg, mKIAA0817 |
| Gene |
UniProtKB-ID:
MEGF8_MOUSE
UniprotKB:
P60882
UniParc:
UPI000176A12C
EMBL:
EU723517,
BC051121,
AK122377,
AK030408,
BC031185,
BC060277,
BC036727
Ensembl:
ENSMUSG00000045039
KO:
mmu:269878
|
| Nucleutide sequences |
EMBL-CDS:
AAH36727.1,
ACE00231.1,
AAH31185.1,
BAC26949.1,
BAC65659.1,
AAH60277.1,
AAH51121.1
Ensembl_TRS:
ENSMUST00000128119
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000122192
RefSeq:
NP_001153872.1
|
| Others |
UniRef100:
UniRef100_P60882
UniRef90:
UniRef90_P60882
UniRef50:
UniRef50_Q7Z7M0
UniGene:
Mm.38527
CCDS:
CCDS52148.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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