| Type | Description |
|---|---|
| Definition | SPO11 meiotic protein covalently bound to DSB |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:31:00 | Combinatorial control of Spo11 alternative splicing by modulation of RNA polymerase II dynamics and splicing factor recruitment during meiosis. | 32303676 |
| 2020-10-03 12:54:00 | A segregating human allele of SPO11 modeled in mice disrupts timing and amounts of meiotic recombination, causing oligospermia and a decreased ovarian reservedagger. | 31074776 |
| 2020-04-25 10:49:00 | ATM and PRDM9 regulate SPO11-bound recombination intermediates during meiosis. | 32051414 |
| 2017-08-26 11:14:00 | These data suggest that Tex19.1 and Ubr2 are required for mouse spermatocytes to accumulate sufficient Spo11-dependent recombination to ensure that the homology search is consistently successful, and reveal a hitherto unknown genetic pathway promoting meiotic recombination in mammals. | 28708824 |
| 2017-01-28 11:58:00 | If SPO11 expression is reduced and DNA double-strand breaks at zygonema are decreased (approximately 40 % below wild-type level), meiotic chromosome pairing is normal. | 26440409 |
| Type | IDs |
|---|---|
| Synonymous | AI449549, Spo11a, Spo11b |
| Gene |
UniProtKB-ID:
SPO11_MOUSE
UniprotKB:
Q9WTK8
UniParc:
UPI0000000885,
UPI00000E6448,
UPI0000022C0C,
UPI00000E8398,
UPI0000191E03
EMBL:
AF163054,
AF163049,
AF169386,
AF163053,
AF167439,
AF165313,
AF149309,
AF443910,
AF173848,
AF126400,
AF163052,
AF163051
Ensembl:
ENSMUSG00000005883
KO:
mmu:26972
|
| Nucleutide sequences |
EMBL-CDS:
AAF87096.1,
AAL32063.1,
AAF87094.1,
AAD44811.1,
AAD52563.1,
AAD49561.1,
AAF87090.1,
AAD43592.1,
AAD43588.1,
AAD43589.1,
AAD43591.1
Ensembl_TRS:
ENSMUST00000050442,
ENSMUST00000109126,
ENSMUST00000109125
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000104754,
ENSMUSP00000104753,
ENSMUSP00000059056
RefSeq:
NP_036176.1,
XP_006499682.1,
NP_001077429.1,
XP_006499683.1,
NP_001292363.1,
XP_006499685.1,
XP_006499681.1,
XP_006499680.1,
XP_036018140.1,
XP_036018141.1,
NP_001077428.1
|
| Others |
UniRef100:
UniRef100_Q9WTK8
UniRef90:
UniRef90_Q9WTK8
UniRef50:
UniRef50_Q9WTK8
UniGene:
Mm.23495
CCDS:
CCDS50812.1,
CCDS50811.1,
CCDS17137.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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