| Type | Description |
|---|---|
| Definition | immunoglobulin superfamily containing leucine-rich repeat |
| Date | Results | Publications |
|---|---|---|
| 2020-06-06 11:30:00 | Meflin deficiency led to significant tumor progression with poorly differentiated histology in a PDAC mouse model. Meflin deficiency or low expression resulted in straightened stromal collagen fibers, which represent a signature for aggressive tumors, in mousePDAC tissues. | 31439548 |
| 2020-05-23 11:00:00 | Meflin interacts with bone morphogenetic protein 7. Meflin knockout mice developed marked cardiac interstitial fibrosis with defective compensation mechanisms. | 31221024 |
| 2019-01-12 11:48:00 | Immunoglobulin superfamily containing leucine-rich repeat protein (Islr) interacts with Dishevelled-2 (Dvl2) to activate canonical Wnt signaling. | 30510196 |
| 2016-12-31 11:23:00 | Those results are consistent with a decrease in the number of clonogenic colony-forming unit-fibroblasts within the BM of Meflin-deficient mice. These preliminary data suggest that Meflin is a potential marker for cultured MSCs and their source cells in vivo. | 26924503 |
| Type | IDs |
|---|---|
| Synonymous | AW553146, Meflin |
| Gene |
UniProtKB-ID:
ISLR_MOUSE,
A0A146E664_MOUSE
UniprotKB:
Q6GU68,
A0A146E664
UniParc:
UPI0000025204
EMBL:
BR001381,
BC006602,
AB024538,
AB024539
Ensembl:
ENSMUSG00000037206
KO:
mmu:26968
|
| Nucleutide sequences |
EMBL-CDS:
BAA85973.1,
BAA85972.1,
AAH06602.1,
FAA01193.1
Ensembl_TRS:
ENSMUST00000168864,
ENSMUST00000041477
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000045142,
ENSMUSP00000126963
RefSeq:
XP_006511267.1,
NP_036173.1,
XP_011241052.1,
NP_001182360.1
|
| Others |
UniRef100:
UniRef100_Q6GU68
UniRef90:
UniRef90_Q6GU68
UniRef50:
UniRef50_O14498
UniGene:
Mm.367887
CCDS:
CCDS23237.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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