Type | Description |
---|---|
Definition | chromodomain helicase DNA binding protein 5 |
Date | Results | Publications |
---|---|---|
2018-04-07 10:46:00 | Pyramidal neurons cultured from Chd5(-/-) cortex displayed alterations in dendritic morphology. Paralleling autism spectrum disorder nosology, Chd5(-/-) mice exhibited abnormal sociocommunicative behavior and a strong preference for familiarity. Chd5(-/-) mice further showed deficits in responding to the distress of a conspecific, a mouse homolog of empathy. | 28608855 |
2016-12-17 11:28:00 | Chd5 represses murine endogenous retrovirus-L (MuERV-L/MERVL), an endogenous retrovirus-derived retrotransposon, by regulating H3K27me3 and H3.1/H3.2 function. | 26359639 |
2015-10-03 10:54:00 | Chd5 is a multi-faceted mediator of histone-to-protamine replacement and is important in the cascade of molecular events underlying this process of extensive chromatin remodelling. | 24818823 |
2014-09-06 10:46:00 | Our data indicate that CHD5 is required for normal spermiogenesis, especially for spermatid chromatin condensation. | 24252660 |
2014-06-14 13:04:00 | Chd5 expression is retained at high levels in differentiated neurons of the adult mouse. | 24120991 |
Type | IDs |
---|---|
Synonymous | 4930532L22Rik, AW060752, B230399N07Rik, CHD-5 |
Gene |
UniProtKB-ID:
E9PYU4_MOUSE,
E9PYL1_MOUSE
UniprotKB:
E9PYU4,
E9PYL1
UniParc:
UPI0000604CE5,
UPI0000604CE4
EMBL:
AL611985
Ensembl:
ENSMUSG00000005045
KO:
mmu:269610
|
Nucleutide sequences |
Ensembl_TRS:
ENSMUST00000164662,
ENSMUST00000030775
|
Protein sequencees |
Ensembl_PRO:
ENSMUSP00000132600,
ENSMUSP00000030775
RefSeq:
XP_006538992.1,
XP_006538994.1,
XP_017175733.1,
NP_083492.2,
XP_006538993.1,
XP_006538996.1,
XP_030109449.1,
NP_001074845.1,
NP_001356172.1,
XP_006538998.1
|
Others |
UniRef100:
UniRef100_E9PYL1,
UniRef100_E9PYU4
UniRef90:
UniRef90_A2A8L1
UniRef50:
UniRef50_A2A8L1
UniGene:
Mm.40192
|