| Type | Description |
|---|---|
| Definition | chromodomain helicase DNA binding protein 5 |
| Date | Results | Publications |
|---|---|---|
| 2018-04-07 10:46:00 | Pyramidal neurons cultured from Chd5(-/-) cortex displayed alterations in dendritic morphology. Paralleling autism spectrum disorder nosology, Chd5(-/-) mice exhibited abnormal sociocommunicative behavior and a strong preference for familiarity. Chd5(-/-) mice further showed deficits in responding to the distress of a conspecific, a mouse homolog of empathy. | 28608855 |
| 2016-12-17 11:28:00 | Chd5 represses murine endogenous retrovirus-L (MuERV-L/MERVL), an endogenous retrovirus-derived retrotransposon, by regulating H3K27me3 and H3.1/H3.2 function. | 26359639 |
| 2015-10-03 10:54:00 | Chd5 is a multi-faceted mediator of histone-to-protamine replacement and is important in the cascade of molecular events underlying this process of extensive chromatin remodelling. | 24818823 |
| 2014-09-06 10:46:00 | Our data indicate that CHD5 is required for normal spermiogenesis, especially for spermatid chromatin condensation. | 24252660 |
| 2014-06-14 13:04:00 | Chd5 expression is retained at high levels in differentiated neurons of the adult mouse. | 24120991 |
| Type | IDs |
|---|---|
| Synonymous | 4930532L22Rik, AW060752, B230399N07Rik, CHD-5 |
| Gene |
UniProtKB-ID:
E9PYU4_MOUSE,
E9PYL1_MOUSE
UniprotKB:
E9PYU4,
E9PYL1
UniParc:
UPI0000604CE5,
UPI0000604CE4
EMBL:
AL611985
Ensembl:
ENSMUSG00000005045
KO:
mmu:269610
|
| Nucleutide sequences |
Ensembl_TRS:
ENSMUST00000164662,
ENSMUST00000030775
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000132600,
ENSMUSP00000030775
RefSeq:
XP_006538992.1,
XP_006538994.1,
XP_017175733.1,
NP_083492.2,
XP_006538993.1,
XP_006538996.1,
XP_030109449.1,
NP_001074845.1,
NP_001356172.1,
XP_006538998.1
|
| Others |
UniRef100:
UniRef100_E9PYL1,
UniRef100_E9PYU4
UniRef90:
UniRef90_A2A8L1
UniRef50:
UniRef50_A2A8L1
UniGene:
Mm.40192
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员