| Type | Description |
|---|---|
| Definition | HMG-box transcription factor 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:25:00 | Suppression of p38/HBP1 pathway alleviates hyperosmotic stress-induced senescent progression of chondrocyte senescence. | 32549582 |
| 2020-03-21 10:10:00 | Reduced HBP1 expression and subsequent MMP-13 upregulation may play a pivotal role in the invasiveness of oral cancer. | 30191992 |
| 2019-12-14 12:35:00 | MDM2 facilitates HBP1 proteasomal degradation by ubiquitinating HBP1, regardless of p53 status, thus attenuating the transcriptional inhibition of HBP1 in the expression of its target genes, such as the DNA methyltransferase DNMT1 and histone methyltransferase EZH2, which results in global DNA hypermethylation and histone hypermethylation and ultimately genome instability. | 30816344 |
| 2019-11-02 10:50:00 | Our experiment also verified the target relationship between miR-21 and HBP1. MiR-21 may affect migration and invasion ability of drug-resistant lung adenocarcinoma cells by targeting HBP1, therefore modulating EMT. | 29663730 |
| 2019-07-20 11:25:00 | HBP1 functions as a tumor suppressor, and its ectopic expression hindered cell proliferation of non-small-cell lung cancer (NSCLC). AFAP1-AS1 repressed HBP1 expression by recruiting LSD1 to the HBP1 promoter regions in NSCLC cell lines. | 31069893 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
HBP1_HUMAN,
A0A024R722_HUMAN,
B4DJ36_HUMAN
UniprotKB:
O60381,
A0A024R722,
B4DJ36
UniParc:
UPI000006DC04,
UPI000020F8E2,
UPI0000073EE0,
UPI00003CF22F
EMBL:
AF182038,
AK122785,
BC017069,
AC004492,
CH471070,
AK074353,
AK295910,
BC022329
Ensembl:
ENSG00000105856,
ENSG00000283847
KO:
hsa:26959
|
| Nucleutide sequences |
EMBL-CDS:
AAH17069.1,
AAC08317.1,
BAG53729.1,
EAW83392.1,
AAD56225.1,
AAH22329.1,
BAB85059.1,
EAW83394.1,
BAG58698.1
Gene_ORFName:
hCG_17934
Ensembl_TRS:
ENST00000485846,
ENST00000640195,
ENST00000222574,
ENST00000638303,
ENST00000638893,
ENST00000468410
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000222574,
ENSP00000492343,
ENSP00000418738,
ENSP00000420500,
ENSP00000491311,
ENSP00000492167
RefSeq:
XP_024302481.1,
NP_001231191.1,
XP_005250324.1,
XP_016867456.1,
XP_005250323.1,
NP_036389.2,
XP_024302482.1
|
| Others |
UniRef100:
UniRef100_O60381
UniRef90:
UniRef90_O60381
UniRef50:
UniRef50_O60381
UniGene:
Hs.162032
CCDS:
CCDS5741.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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