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269523 Vcp

269523

Vcp

valosin containing protein

protein-coding

Mus musculus

基因描述

Type Description
Definition valosin containing protein

研究结论

Date Results Publications
2020-09-26 13:03:00 Expression level of R155H mRNA in the knock-in mouse model. 31973812
2020-06-20 10:54:00 The study identifies VCP as central mediator of both lysosomal clearance and biogenesis in skeletal muscle. 30654731
2020-06-06 13:15:00 First evidence for a novel function of VCP in meiotic arrest of mouse oocytes. 30476006
2020-05-23 10:07:00 Pathogenic mutations in the ALS gene CCNF cause cytoplasmic mislocalization of Cyclin F and elevated VCP ATPase activity 31577344
2019-10-19 10:58:00 we demonstrate that disrupted expression of the core autophagy proteins ULK1 and ULK2 in mice causes a vacuolar myopathy with ubiquitin and TDP-43-positive inclusions; this myopathy is similar to that caused by VCP/p97 mutations, the most common cause of familial inclusion body myopathy (IBM) 30979586

名称对应

Type IDs
Synonymous 3110001E05, CDC48, p97, p97/VCP
Gene
UniProtKB-ID: TERA_MOUSE
UniprotKB: Q01853
UniParc: UPI000005FB2E
EMBL: AK159509, AL672276, BC043053, AK159177, AK149931, BC049114, AK151109, AK153249, Z14044, AK028264, AK169140, AK030751, AK151418, AK167794
Ensembl: ENSMUSG00000028452
KO: mmu:269523
Nucleutide sequences
EMBL-CDS: AAH43053.1, BAC27119.1, AAH49114.1, BAE39824.1, BAE30119.1, BAE30383.1, CAA78412.1, BAE29175.1, BAE40919.1, BAE34876.1, BAE31840.1, BAE35141.1, BAC25849.1
Ensembl_TRS: ENSMUST00000030164
Protein sequencees
Ensembl_PRO: ENSMUSP00000030164
RefSeq: NP_033529.3
Others
UniRef100: UniRef100_P55072
UniRef90: UniRef90_P55072
UniRef50: UniRef50_P55072
UniGene: Mm.245976
CCDS: CCDS18086.1

全选

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研究热度

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