| Type | Description |
|---|---|
| Definition | leucine-rich repeats and immunoglobulin-like domains 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-04-04 11:43:00 | Mice with homozygous mutations in either Lrig2 or Hpse2 had increased nerve density within the urinary bladder body and decreased nerve density around the urinary outflow tract. Observations provide evidence that a peripheral neuropathy is central to the pathobiology of functional bladder outlet obstruction in urofacial syndrome and emphasize the importance of LRIG2 and Hpse2 for nerve patterning in the urinary tract. | 30885509 |
| 2016-04-16 10:10:00 | Lrig2 has a role in negative regulation of ectodomain shedding of axon guidance receptors by ADAM17 protease | 26651291 |
| 2014-04-12 10:46:00 | phenotype of Lrig2E12-/- mice showed that Lrig2 was a promoter of PDGFB-induced glioma | 24023893 |
| 2014-03-22 10:04:00 | At later stages, Lrig1 expression is sustained in non-sensory tissues, whereas Lrig2 levels are enhanced in neurons and sensory epithelia | 24086156 |
| Type | IDs |
|---|---|
| Synonymous | 4632419I10Rik, BB096938, LIG-2 |
| Gene |
UniProtKB-ID:
LRIG2_MOUSE,
B2RRI5_MOUSE
UniprotKB:
Q52KR2,
B2RRI5
UniParc:
UPI00001C2D27,
UPI000523F1A4,
UPI0000193D6E
EMBL:
AK173030,
BC094228,
AC124741,
BC138422,
AC146300
Ensembl:
ENSMUSG00000032913
KO:
mmu:269473
|
| Nucleutide sequences |
EMBL-CDS:
BAD32308.1,
AAH94228.1,
AAI38423.1
Ensembl_TRS:
ENSMUST00000046316,
ENSMUST00000199070,
ENSMUST00000198332
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000035999,
ENSMUSP00000142373,
ENSMUSP00000142540
RefSeq:
NP_001297627.1,
XP_030108494.1,
NP_001020238.1,
XP_006501607.1,
XP_017175091.1,
XP_036019020.1
|
| Others |
UniRef100:
UniRef100_B2RRI5,
UniRef100_Q52KR2
UniRef90:
UniRef90_Q52KR2
UniRef50:
UniRef50_Q52KR2
UniGene:
Mm.34855
CCDS:
CCDS17701.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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