| Type | Description |
|---|---|
| Definition | transient receptor potential cation channel, subfamily C, member 7 |
| Date | Results | Publications |
|---|---|---|
| 2018-05-19 11:56:00 | The injury phase after myocardial infarcts occurs during reperfusion and is a consequence of calcium release from internal stores combined with calcium entry, leading to cell death. We identify canonical transient receptor potential channels (TRPC) 3/6/7 as the cation channels through which most of the damaging calcium enters cells to trigger their death, and we describe mechanisms activated during the injury phase. | 28526717 |
| 2014-10-04 10:58:00 | TRPC7 is intimately involved in the initiation of seizures both in vitro and in vivo. | 25049394 |
| 2011-07-02 10:19:00 | These results demonstrate that the melanopsin-evoked depolarization in retinal ganglion cells is not mediated by either TRPC3, TRPC6 or TRPC7 channel subunits alone. | 21261756 |
| 2010-05-31 11:23:00 | TRPC channels are necessary mediators of pathologic cardiac hypertrophy, in part through a calcineurin-NFAT signaling pathway | 20351294 |
| Type | IDs |
|---|---|
| Synonymous | TRP7, Trrp8 |
| Gene |
UniProtKB-ID:
TRPC7_MOUSE,
Q3UXW9_MOUSE,
Q0VFY2_MOUSE,
E9PVJ9_MOUSE
UniprotKB:
Q9WVC5,
Q3UXW9,
Q0VFY2,
E9PVJ9
UniParc:
UPI00015AA06A,
UPI0000028FEF,
UPI00005ABB64
EMBL:
AC132886,
AK135153,
BC117995,
AF139923,
AC132322
Ensembl:
ENSMUSG00000021541
KO:
mmu:26946
|
| Nucleutide sequences |
EMBL-CDS:
AAD42069.1,
BAE22444.1,
AAI17996.1
Ensembl_TRS:
ENSMUST00000022023,
ENSMUST00000109871
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000022023,
ENSMUSP00000105497
RefSeq:
XP_036013952.1,
XP_006517325.1,
XP_006517326.1,
NP_001289302.1,
NP_036165.1,
NP_001289301.1,
XP_006517327.1
|
| Others |
UniRef100:
UniRef100_Q3UXW9,
UniRef100_Q9WVC5,
UniRef100_E9PVJ9
UniRef90:
UniRef90_Q9WVC5
UniRef50:
UniRef50_Q9HCX4
UniGene:
Mm.62409
CCDS:
CCDS26566.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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