| Type | Description |
|---|---|
| Definition | phospholipase C, eta 1 |
| Date | Results | Publications |
|---|---|---|
| 2013-06-01 10:42:00 | Study concludes that perinuclear PLCepsilon, scaffolded to mAKAP in cardiac myocytes, responds to hypertrophic stimuli to generate diacylglycerol (DAG) from PI4P in the Golgi apparatus, in close proximity to the nuclear envelope, to regulate activation of nuclear PKD and hypertrophic signaling pathways. | 23540699 |
| 2011-08-13 10:49:00 | Phospholipase C-eta was found to be expressed in mouse beta-cells, and knockout of that gene disrupts the action of exendin-4 to facilitate calcium-induced calcium release in the beta-cells of these mice. | 21041529 |
| 2011-07-02 10:19:00 | PLC-eta1 is activated via intracellular calcium mobilization from the endoplasmic reticulum, and therefore amplifies G-protein coupled receptor mediated signaling | 21262355 |
| 2010-01-21 00:00:00 | molecular cloning of PLC-eta1 and PLC-eta2. | 15583837 |
| 2010-01-21 00:00:00 | The identification of a novel PLC isoform in the brains of human and mouse, named PLC-eta, which contains the conserved pleckstrin homology domain, X and Y domains for catalytic activity and the C2 domain. | 15702972 |
| Type | IDs |
|---|---|
| Synonymous | BC042549, PLC-eta-1, PLCeta1, Plcl3 |
| Gene |
UniProtKB-ID:
PLCH1_MOUSE,
H3BKK4_MOUSE
UniprotKB:
Q4KWH5,
H3BKK4
UniParc:
UPI000053F650,
UPI00001B2E01,
UPI00003564F0,
UPI000053F652,
UPI000053F651,
UPI00000E8F98
EMBL:
BC042549,
BC055005,
AY691173,
AC116732,
AY691174,
BC052372,
AK173095,
AC121285,
AY691172
Ensembl:
ENSMUSG00000036834
KO:
mmu:269437
|
| Nucleutide sequences |
EMBL-CDS:
AAH42549.1,
AAH52372.1,
AAW22611.1,
AAH55005.1,
AAW22610.1,
BAD32373.1,
AAW22609.1
Ensembl_TRS:
ENSMUST00000159676,
ENSMUST00000162269,
ENSMUST00000084105,
ENSMUST00000177143
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000124463,
ENSMUSP00000081122,
ENSMUSP00000124632,
ENSMUSP00000135424
RefSeq:
NP_001357913.1,
XP_006501604.1,
XP_030108493.1,
NP_001357914.1,
NP_001171204.1,
XP_011238435.1,
XP_036019019.1,
XP_011238436.1,
XP_017175082.1,
XP_006501601.1,
XP_017175090.1,
XP_006501599.1,
XP_011238433.1,
XP_030108492.1,
XP_006501598.1,
XP_006501596.1,
XP_017175084.1,
XP_006501593.1,
XP_017175089.1,
NP_899014.2,
XP_017175087.1,
XP_006501594.1,
XP_017175083.1,
XP_017175088.1,
NP_001171203.1,
XP_017175085.1
|
| Others |
UniRef100:
UniRef100_H3BKK4,
UniRef100_Q4KWH5
UniRef90:
UniRef90_Q4KWH5
UniRef50:
UniRef50_Q4KWH5
UniGene:
Mm.316391
CCDS:
CCDS38444.2,
CCDS50918.1,
CCDS57215.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员