| Type | Description |
|---|---|
| Definition | regulator of telomere elongation helicase 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-01-19 11:14:00 | Rtel1 binds to and inhibits restart of reversed replication forks within telomeres, which compromises replication and leads to critically short telomeres. | 29290468 |
| 2013-11-16 11:20:00 | RTEL1 plays a critical role in both telomere and genome-wide replication, which is crucial for genetic stability and tumor avoidance. | 24115439 |
| 2013-01-26 11:18:00 | Upregulated RTEL1 is tumorigenic and is able to initiate the formation of hepatocellular carcinoma in mice. | 22238064 |
| 2012-12-22 11:42:00 | propose that mRtel1 is a key protein for DNA replication, recombination, and repair and efficient elongation of telomeres by telomerase | 22593209 |
| 2012-07-07 11:57:00 | RTEL1 performs two distinct functions at telomeres: it disassembles T loops and also counteracts telomeric G4-DNA structures, which together ensure the dynamics and stability of the telomere. | 22579284 |
| Type | IDs |
|---|---|
| Synonymous | AI451565, AW540478, Rtel |
| Gene |
UniProtKB-ID:
RTEL1_MOUSE
UniprotKB:
Q0VGM9
UniParc:
UPI0000566C00,
UPI0000D77A3B,
UPI00004766FB,
UPI00005AC3C2,
UPI0000216A91,
UPI000058B13B
EMBL:
AY481622,
AY481621,
AL928965,
BC105578,
AK145145,
AY481619,
AY481620,
AY481623,
BC144977,
BC145658,
AK173097,
BC144978
Ensembl:
ENSMUSG00000038685
KO:
mmu:269400
|
| Nucleutide sequences |
EMBL-CDS:
CAM26418.1,
BAD32375.1,
CAM26414.1,
AAR27236.1,
AAI44979.1,
AAI44978.1,
CAM26417.1,
AAR27237.1,
AAR27235.1,
CAM26416.1,
CAM26413.1,
AAI05579.1,
AAI45659.1,
AAR27238.1,
BAE26258.1,
CAM26415.1,
AAR27234.1
Ensembl_TRS:
ENSMUST00000048608,
ENSMUST00000108815,
ENSMUST00000054622,
ENSMUST00000108814,
ENSMUST00000098971
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000104443,
ENSMUSP00000043563,
ENSMUSP00000104442,
ENSMUSP00000053120,
ENSMUSP00000096571
RefSeq:
XP_006500704.1,
XP_006500705.1,
NP_001001882.3,
XP_006500703.1,
NP_001160137.1,
XP_006500700.1,
NP_001160140.1,
XP_006500696.1,
NP_001160139.1,
NP_001350000.1,
NP_001160138.1
|
| Others |
UniRef100:
UniRef100_Q0VGM9
UniRef90:
UniRef90_Q0VGM9
UniRef50:
UniRef50_Q0VGM9
UniGene:
Mm.11333
CCDS:
CCDS50850.1,
CCDS50852.1,
CCDS50849.1,
CCDS50851.1,
CCDS17208.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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