| Type | Description |
|---|---|
| Definition | apoptosis-inducing factor, mitochondrion-associated 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:17:00 | Overexpression of apoptosis inducing factor aggravates hypoxic-ischemic brain injury in neonatal mice. | 32001673 |
| 2020-09-12 15:04:00 | The authors show that deletion of apoptosis-inducing factor (AIF) in a KrasG12D-driven mouse lung cancer model resulted in a marked survival advantage, with delayed tumor onset and decreased malignant progression. | 31133695 |
| 2019-11-16 11:26:00 | These results indicate that AIF2 deficiency exacerbates free radical production and HI-induced neonatal brain injury. | 30584234 |
| 2019-09-21 11:15:00 | data reveal that the mitochondrial signals regulated by AIF are critical to hematopoietic decision-making. Emerging as a link between mitochondrial metabolism and hematopoietic cell fate, AIF-mediated OXPHOS regulation represents a target for the development of new immunomodulatory therapeutics. | 29323266 |
| 2019-05-25 12:15:00 | we provide evidence that the disease-associated apoptosis-inducing factor (AIF) deletion arginine 201 (R200 in rodents) causes pathology in knockin mice. Aifm1 (R200 del) knockin mice manifest peripheral neuropathy. | 29780003 |
| Type | IDs |
|---|---|
| Synonymous | AIF, AIFsh2, Hq, Pdcd8 |
| Gene |
UniProtKB-ID:
AIFM1_MOUSE,
B1AU25_MOUSE
UniprotKB:
Q9Z0X1,
B1AU25
UniParc:
UPI0000001842,
UPI00001F8219,
UPI0000D676C6
EMBL:
BC003292,
AF100927,
DQ016499,
AL669901
Ensembl:
ENSMUSG00000036932
KO:
mmu:26926
|
| Nucleutide sequences |
EMBL-CDS:
AAY84740.1,
AAD16435.1,
AAH03292.1
Ensembl_TRS:
ENSMUST00000037349,
ENSMUST00000114945
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000041104,
ENSMUSP00000110595
RefSeq:
NP_036149.1,
NP_001277293.1
|
| Others |
UniRef100:
UniRef100_Q9Z0X1,
UniRef100_B1AU25
UniRef90:
UniRef90_Q9Z0X1
UniRef50:
UniRef50_O95831
UniGene:
Mm.240434
CCDS:
CCDS30109.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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