Mecr - mitochondrial trans-2-enoyl-CoA reductase-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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26922 Mecr

基因描述

Type	Description
Definition	mitochondrial trans-2-enoyl-CoA reductase

研究结论

Date	Results	Publications
2021-04-03 13:29:00	ATP reduces mitochondrial MECR protein in liver of diet-induced obese mice in mechanism of insulin resistance.	32440681
2010-01-21 00:00:00	The results showed a ventricular dilatation behind impaired heart function upon Mecr overexpression, concurrent with appearance of dysmorphic mitochondria	19440339

名称对应

Type	IDs
Synonymous	AI195831, NRBF-1, Nrbf1
Gene	UniProtKB-ID: MECR_MOUSE UniprotKB: Q9DCS3 UniParc: UPI0000023032 EMBL: AK002533, BC003864 Ensembl: ENSMUSG00000028910 KO: mmu:26922
Nucleutide sequences	EMBL-CDS: BAB22169.1, AAH03864.1 Ensembl_TRS: ENSMUST00000030742
Protein sequencees	Ensembl_PRO: ENSMUSP00000030742 RefSeq: XP_036020030.1, XP_006538948.1, XP_036020031.1, XP_011248564.1, XP_011248565.1, XP_006538952.1, NP_079573.2, XP_011248563.1
Others	UniRef100: UniRef100_Q9DCS3 UniRef90: UniRef90_Q9Z311 UniRef50: UniRef50_Q9BV79-2 UniGene: Mm.192706 CCDS: CCDS18715.1

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
32440681	ATP reduces mitochondrial MECR protein in liver of diet-induced obese mice in mechanism of insulin resistance. Biosci Rep Shengnan Qian , Li Ma , Shiqiao Peng , Yanhong Xu , Kaiyue Wu , Shuang Shen , Xiaoying Zhang , Yongning Sun , Jianping Ye	2020-06-26	-
32325033	BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Cell Syst Reza Pourhaghighi , Peter E A Ash , Sadhna Phanse , Florian Goebels , Lucas Z M Hu , Siwei Chen , Yingying Zhang , Shayne D Wierbowski , Samantha Boudeau , Mohamed T Moutaoufik , Ramy H Malty , Edyta Malolepsza , Kalliopi Tsafou , Aparna Nathan , Graham Cromar , Hongbo Guo , Ali Al Abdullatif , Daniel J Apicco , Lindsay A Becker , Aaron D Gitler , Stefan M Pulst , Ahmed Youssef , Ryan Hekman , Pierre C Havugimana , Carl A White , Benjamin C Blum , Antonia Ratti , Camron D Bryant , John Parkinson , Kasper Lage , Mohan Babu , Haiyuan Yu , Gary D Bader , Benjamin Wolozin , Andrew Emili	2020-04-22	-
30266742	Impaired Mitochondrial Fatty Acid Synthesis Leads to Neurodegeneration in Mice. J. Neurosci. Remya R Nair , Henna Koivisto , Kimmo Jokivarsi , Ilkka J Miinalainen , Kaija J Autio , Aki Manninen , Pekka Poutiainen , Heikki Tanila , J Kalervo Hiltunen , Alexander J Kastaniotis	2018-11-07	-
28369354	Genetic modifications of Mecr reveal a role for mitochondrial 2-enoyl-CoA/ACP reductase in placental development in mice. Hum. Mol. Genet. Remya R Nair , Juha M KerÃ¤tÃ¤r , Kaija J Autio , Ali J Masud , Mikko A J FinnilÃ¤ , Helena I Autio-Harmainen , Ilkka J Miinalainen , Pentti A Nieminen , J Kalervo Hiltunen , Alexander J Kastaniotis	2017-06-01	-
27480124	Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA. BMC Immunol. Xiaoyun Liu , Yan Jiao , Yanhong Cao , Nan Deng , Yonghui Ma , Karen A Hasty , Andrew Kang , Hong Chen , John M Stuart , Weikuan Gu	2016-08-02	-
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
21677750	A conditional knockout resource for the genome-wide study of mouse gene function. Nature William C Skarnes , Barry Rosen , Anthony P West , Manousos Koutsourakis , Wendy Bushell , Vivek Iyer , Alejandro O Mujica , Mark Thomas , Jennifer Harrow , Tony Cox , David Jackson , Jessica Severin , Patrick Biggs , Jun Fu , Michael Nefedov , Pieter J de Jong , A Francis Stewart , Allan Bradley	2011-06-15	-
21267068	A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. Graciana Diez-Roux , Sandro Banfi , Marc Sultan , Lars Geffers , Santosh Anand , David Rozado , Alon Magen , Elena Canidio , Massimiliano Pagani , Ivana Peluso , Nathalie Lin-Marq , Muriel Koch , Marchesa Bilio , Immacolata Cantiello , Roberta Verde , Cristian De Masi , Salvatore A Bianchi , Juliette Cicchini , Elodie Perroud , Shprese Mehmeti , Emilie Dagand , Sabine Schrinner , Asja NÃ¼rnberger , Katja Schmidt , Katja Metz , Christina Zwingmann , Norbert Brieske , Cindy Springer , Ana Martinez Hernandez , Sarah Herzog , Frauke Grabbe , Cornelia Sieverding , Barbara Fischer , Kathrin Schrader , Maren Brockmeyer , Sarah Dettmer , Christin Helbig , Violaine Alunni , Marie-Annick Battaini , Carole Mura , Charlotte N Henrichsen , Raquel Garcia-Lopez , Diego Echevarria , Eduardo Puelles , Elena Garcia-Calero , Stefan Kruse , Markus Uhr , Christine Kauck , Guangjie Feng , Nestor Milyaev , Chuang Kee Ong , Lalit Kumar , MeiSze Lam , Colin A Semple , Attila Gyenesei , Stefan Mundlos , Uwe Radelof , Hans Lehrach , Paolo Sarmientos , Alexandre Reymond , Duncan R Davidson , Pascal DollÃ© , Stylianos E Antonarakis , Marie-Laure Yaspo , Salvador Martinez , Richard A Baldock , Gregor Eichele , Andrea Ballabio	2011-01-18	-
19440339	Myocardial overexpression of Mecr, a gene of mitochondrial FAS II leads to cardiac dysfunction in mouse. PLoS One Zhijun Chen , Hanna Leskinen , Erkki Liimatta , Raija T Sormunen , Ilkka J Miinalainen , Ilmo E Hassinen , J Kalervo Hiltunen	2009-01-01	-
18614015	A mitochondrial protein compendium elucidates complex I disease biology. Cell David J Pagliarini , Sarah E Calvo , Betty Chang , Sunil A Sheth , Scott B Vafai , Shao-En Ong , Geoffrey A Walford , Canny Sugiana , Avihu Boneh , William K Chen , David E Hill , Marc Vidal , James G Evans , David R Thorburn , Steven A Carr , Vamsi K Mootha	2008-07-11	Acacb, Hscb, Gadd45gip1, Lars2, Acad11, Chchd10, Nt5dc3, Slc25a41, Nt5m, Cyp27a1, Acly, Ndufb11, Gldc, Rexo2, Rars, Aldh6a1, Slc25a47, Rdh14, Ppif, Ldhal6b, Me2, Glyat, Slc25a45, Acaca, Nt5c3, Mrpl10, Mrpl41, Mrpl30, Aldh1l1, Mthfs, Shmt2, Atic, Mthfd1, Mat2b, Fam210a, Gpt2, Lyrm2, Rdh13, Mtrf1l, Atad3a, Rars2, Sccpdh, Me3, Maob, Dut, Cyp11b1, Fdps, Akr7a5, Msra, Krt5, Cox6b1, Qdpr, Acat1, Acat2, Aldh7a1, Pcca, Etfb, Etfa, Nudt19, Acadl, Acadm, Acadvl, Acaa1a, Acads, Aco1, Aco2, Prosc, Afg3l1, Adsl, Agxt, Ak2, Ak4, Akap1, Alas1, Alas2, Abcd1, Aldh2, Aldh3a2, Gfer, Acsm1, Slc25a4, Slc25a5, Prdx3, Prdx6, Mrps2, Arg2, Rhoa, Atp5a1, Atp5b, Atp5c1, Atp5f1, Atp5g1, Atp5j, Atp5k, Atpif1, Auh, Akr1b7, Bad, Bak1

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