| Type | Description |
|---|---|
| Definition | growth hormone releasing hormone receptor |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:29:00 | Structural basis for activation of the growth hormone-releasing hormone receptor. | 33060564 |
| 2020-07-18 11:37:00 | Study investigated the signaling axis of GHRH-R and found evidence showing how GHRH-R is up-regulated after stimulation of LPS in human ciliary epithelial cells and the contribution of a noncanonical signaling axis of GHRH-R that involves JAK2 and in acute ocular inflammation. | 32123064 |
| 2020-03-14 11:33:00 | The finding that 8% of IGHD cases without GH1 mutations are explained by GHRHR molecular defects (including missense mutations), together with the high proportion of sporadic cases among those patients, has important implications for genetic counseling. | 31231873 |
| 2020-02-15 10:55:00 | Our results demonstrate a direct action of LPS on ciliary and iris epithelial cells to produce pro-inflammatory factors through a GHRH-R mediated mechanism, and suggest a role of these epithelial cells, in addition to the resident antigen presenting cells, in immune surveillance of the eye. Infiltrating leukocytes may enhance these inflammatory responses by regulating GHRH-R in ciliary and iris epithelial cells, in additi | 30831084 |
| 2019-03-16 11:04:00 | Deletion at the GHRHR gene locus mediated by Alu specific microhomology is associated with isolated growth hormone deficiency. | 30390533 |
| Type | IDs |
|---|---|
| Synonymous | GHRFR, GRFR, IGHD1B, IGHD4 |
| Gene |
UniProtKB-ID:
GHRHR_HUMAN,
A0A090N8Y6_HUMAN
UniprotKB:
Q02643,
A0A090N8Y6
UniParc:
UPI0000061EE1
EMBL:
U42222,
AY557192,
CH471073,
AC005155,
AB065701,
L09237,
L01406,
U42225,
U42224,
AACC02000087,
U42223
Ensembl:
ENSG00000106128
KO:
hsa:2692
|
| Nucleutide sequences |
EMBL-CDS:
AAS59864.1,
AAA35890.1,
AAA58619.1,
AAB37758.1,
AAC23789.1,
BAC05924.1,
EAW93977.1,
EAL24445.1
Gene_ORFName:
tcag7.683,
hCG_37325
Ensembl_TRS:
ENST00000326139
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000320180
RefSeq:
NP_000814.2
|
| Others |
UniRef100:
UniRef100_Q02643
UniRef90:
UniRef90_Q02643
UniRef50:
UniRef50_Q02643
UniGene:
Hs.767,
Hs.733003
CCDS:
CCDS5432.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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