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2691 GHRH

2691

GHRH

growth hormone releasing hormone

protein-coding

Homo sapiens

基因描述

Type Description
Definition growth hormone releasing hormone

研究结论

Date Results Publications
2021-04-03 13:38:00 A comprehensive contribution of genetic variations of the insulin-like growth factor 1 signalling pathway to stroke susceptibility. 32065979
2020-11-21 13:29:00 Structural basis for activation of the growth hormone-releasing hormone receptor. 33060564
2019-08-24 10:17:00 Study in Han Chinese population revealed that rs3755792 and rs7624906 variants at in smoking population and rs3755792 in drinking population presented significant association with hypertension incidence. rs6032470 at GHRH had a statistical association with ischemic stroke incidence in smoking population. 29426577
2019-07-27 11:34:00 GHRH expression was significantly increased in patients with temporal lobe epilepsy. Coimmunoprecipitation confirmed that GHRH interacted with GABAAalpha1 and GABAAbeta2 + 3. GHRH may play an important role in inhibiting seizures by activating GABAARs. 29273763
2019-03-16 12:05:00 P53 can suppress inflammation in a plethora of human tissues. Growth Hormone - is a hypothalamic peptide with a great capacity to affect the complex networks of cellular regulation via GHRH - specific receptors. GHRH antagonistic and agonistic analogs have been developed for clinical applications 30344124

名称对应

Type IDs
Synonymous GHRF, GRF, INN
Gene
UniProtKB-ID: SLIB_HUMAN
UniprotKB: P01286
UniParc: UPI00000534AE, UPI0000156C0A
EMBL: BC098161, BC098109, L00137, X00094, AL031659, L00136, L00135, L00134, BC099727, L29177
Ensembl: ENSG00000118702
KO: hsa:2691
Nucleutide sequences
EMBL-CDS: AAA52608.1, CAA24955.1, AAH99727.1, AAH98161.1, AAA52609.1, CAA24956.1, AAH98109.1
Ensembl_TRS: ENST00000237527, ENST00000373611, ENST00000373614
Protein sequencees
Ensembl_PRO: ENSP00000362716, ENSP00000237527, ENSP00000362713
RefSeq: NP_066567.1, NP_001171660.1
Others
UniRef100: UniRef100_P01286
UniRef90: UniRef90_P01286
UniRef50: UniRef50_P01286
UniGene: Hs.37023
CCDS: CCDS54460.1, CCDS13292.1

全选

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