例如:"NBL1", "4681", "drought"
收藏
26909 Exo1

26909

Exo1

exonuclease 1

protein-coding

Mus musculus

基因描述

Type Description
Definition exonuclease 1

研究结论

Date Results Publications
2020-01-18 10:11:00 Calcium-stimulated AMPK-dependent phosphorylation of Exo1 protects stressed replication forks from aberrant resection. 31053472
2019-12-07 10:14:00 It has been found that deletion of 53BP1 can relieve several of the repair deficiencies observed in B-cells lacking BLM and Exo1, just as it does in cells lacking BRCA1. 29620483
2019-02-16 12:21:00 mice homozygous for a point mutation (D173A) in Exo1 that eliminates its nuclease activity but retains its native conformation, shows a level of trinucleotide expansion that is intermediate between Exo1+/+ and Exo1-/- animals. 30312299
2017-12-30 10:47:00 like canonical DNA mismatch-repair proteins, EXO1 can restrain aberrant homologous recombination events between diverged sequence elements in the genome. 28711786
2015-12-19 12:02:00 The results establish a key role for EXO1 in modulating the severity of hypomorphic MRE11 complex mutations. 26160886

名称对应

Type IDs
Synonymous 5730442G03Rik, Msa
Gene
UniProtKB-ID: EXO1_MOUSE
UniprotKB: Q9QZ11
UniParc: UPI00000E8870
EMBL: AK166425, AK028728, BC006671, AJ238213
Ensembl: ENSMUSG00000039748
KO: mmu:26909
Nucleutide sequences
EMBL-CDS: CAB51863.1, AAH06671.1, BAE38768.1, BAC26086.1
Ensembl_TRS: ENSMUST00000039725
Protein sequencees
Ensembl_PRO: ENSMUSP00000039376
RefSeq: NP_036142.2, XP_030110359.1, XP_006496925.1
Others
UniRef100: UniRef100_Q9QZ11
UniRef90: UniRef90_Q9QZ11
UniRef50: UniRef50_Q9QZ11
UniGene: Mm.283046
CCDS: CCDS15551.1

全选

{{proteinIndex+1}}
mRNA Protein UniprotKB Description
Refseq {{protein.nucleotideVersion}}

Ensembl: {{protein.nucleotideEnsembl}}

{{protein.proteinVersion}}

Ensembl: {{protein.proteinEnsembl}}

{{uniprot}}
Definition: {{{protein.definition}}}

Transcript Veriant:{{protein.transcriptVeriant}}

Status: {{protein.status}}

Location ( {{protein.positionStart}}..{{protein.positionEnd}} )

暂无数据

研究热度

热点单位
排名 科研单位 文献
{{affIndex+1}}

{{aff.value}}

{{aff.size}}

目前还没有研究热点单位

热点人员
排名 研究人员 文献
{{authorIndex+1}}

{{author.value}}

{{author.size}}

目前还没有研究热点人员