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26908 Eif2s3y

26908

Eif2s3y

eukaryotic translation initiation factor 2, subunit 3, structural gene Y-linked

protein-coding

Mus musculus

基因描述

Type Description
Definition eukaryotic translation initiation factor 2, subunit 3, structural gene Y-linked

研究结论

Date Results Publications
2020-12-12 13:22:00 Eif2s3y regulates the proliferation of spermatogonial stem cells via Wnt6/-catenin signaling pathway. 32621839
2017-12-02 11:02:00 Study highlighted novel roles of EIF2S3Y in the pluripotency maintenance and proliferation control of ES cells, which would provide an efficient model to study germ cell generation as well as cancer development using ES cells. 26863630
2016-02-13 10:45:00 Eif2s3y can be replaced by transgenic overexpression of its X chromosome-encoded homolog Eif2s3x. This finding supports the existence of functional redundancy between the Y chromosome genes and their homologs encoded on other chromosomes. 26823431
2014-01-25 10:37:00 this study demonstrates that live mouse progeny can also be generated by using germ cells from males with the Y chromosome contribution limited to only two genes, the testis determinant factor Sry and the spermatogonial proliferation factor Eif2s3y. 24263135
2013-03-09 11:26:00 Data from knockout mice suggest that spermiogenesis can be initiated whether or not second meiotic division has taken place, and even when the only Y genes present are Eif2s3y and Sry. 22869781

名称对应

Type IDs
Synonymous Eif-2gy, Spy, Tfy
Gene
UniProtKB-ID: IF2H_MOUSE
UniprotKB: Q9Z0N2
UniParc: UPI000000B35E
EMBL: BC043656, AJ006584
Ensembl: ENSMUSG00000069049
KO: mmu:26908
Nucleutide sequences
EMBL-CDS: AAH43656.1, CAA07097.1
Ensembl_TRS: ENSMUST00000091197
Protein sequencees
Ensembl_PRO: ENSMUSP00000088736
RefSeq: NP_036141.1, XP_006531673.1, XP_030107429.1, XP_011246895.1, NP_001344023.1, XP_036018085.1
Others
UniRef100: UniRef100_Q9Z0N2
UniRef90: UniRef90_Q9Z0N2
UniRef50: UniRef50_Q9Z0N2
UniGene: Mm.250909
CCDS: CCDS30542.1

全选

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