| Type | Description |
|---|---|
| Definition | diacylglycerol lipase, alpha |
| Date | Results | Publications |
|---|---|---|
| 2017-05-07 01:24:00 | Results demonstrate that mice with a deletion of the DAGL-alpha enzyme show a phenotype of increased emotional or stress-related behaviors. This is characterized by a reduced exploration of the central area of the open field, a maternal neglect behavior, a fear extinction deficit, increased behavioral despair, increased anxiety-related behaviors in the light/dark box, and reduced hippocampal neurogenesis | 25981172 |
| 2014-09-13 12:12:00 | Authors demonstrated that phospholipase D and diacylglycerol lipase were required for providing arachidonic acid for prostaglandin E(2) biosynthesis. | 24866789 |
| 2013-05-25 10:32:00 | In corpus striatum diacylglycerol lipase-alpha activity is regulated by calcium/calmodulin dependent protein kinase (CaMK-II). | 23502535 |
| 2010-03-22 11:30:00 | Endocannabinoid 2-arachidonoylglycerol produced by DGLalpha, but not by DGLbeta, mediates retrograde suppression at central synapses. | 20159446 |
| 2010-03-08 12:11:00 | DAGLalpha is the major biosynthetic enzyme for 2-AG in the nervous system and reveal an essential role for this enzyme in regulating retrograde synaptic plasticity and adult neurogenesis. | 20147530 |
| Type | IDs |
|---|---|
| Synonymous | Nsddr |
| Gene |
UniProtKB-ID:
DGLA_MOUSE,
A4FU75_MOUSE
UniprotKB:
Q6WQJ1,
A4FU75
UniParc:
UPI000024E235,
UPI0000F58DDC
EMBL:
AY275376,
AK129183,
BC148308,
BC112414
Ensembl:
ENSMUSG00000035735
KO:
mmu:269060
|
| Nucleutide sequences |
EMBL-CDS:
AAQ17118.1,
BAC97993.1,
AAI48309.1,
AAI12415.1
Ensembl_TRS:
ENSMUST00000039327
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000046358
RefSeq:
XP_036017498.1,
XP_017173702.1,
NP_932782.2
|
| Others |
UniRef100:
UniRef100_Q6WQJ1
UniRef90:
UniRef90_Q6WQJ1
UniRef50:
UniRef50_Q6WQJ1
UniGene:
Mm.329718
CCDS:
CCDS29574.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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