| Type | Description |
|---|---|
| Definition | dysferlin |
| Date | Results | Publications |
|---|---|---|
| 2021-02-13 13:28:00 | Dysferlin-deficient myotubes show tethering of different membrane compartments characterized by TMEM16E and DHPRalpha. | 32736698 |
| 2021-01-09 13:32:00 | Ischemia reperfusion injury provokes adverse left ventricular remodeling in dysferlin-deficient hearts through a pathway that involves TIRAP dependent signaling. | 32839504 |
| 2020-07-18 11:42:00 | These observations indicate that an early manifestation of dysferlin deficiency is the reprogramming of skeletal muscle and adipose tissue lipid metabolism, which is likely to contribute to the progressive adverse histopathology in dysferlinopathies. | 31203232 |
| 2020-07-11 12:36:00 | lipid accumulation in skeletal muscle in dysferlin-deficient mice | 31653658 |
| 2020-01-18 12:04:00 | Muscle hypertrophy occurred in response to increased IGF-1 in mice with and without dysferlin. Male mice showed a more robust response compared with females. Increased IGF-1 did not cause loss of force per cross-sectional area in Dysf(-/-) muscles. We conclude that increased local IGF-1 promotes functional hypertrophy when dysferlin is absent. | 31323135 |
| Type | IDs |
|---|---|
| Synonymous | 2310004N10Rik, AI604795, D6Pas3 |
| Gene |
UniProtKB-ID:
DYSF_MOUSE,
E9Q423_MOUSE,
A0A0N4SUN3_MOUSE,
A0A0N4SUJ2_MOUSE,
E9PXU9_MOUSE,
A0A0N4SWH3_MOUSE,
A0A0N4SV63_MOUSE,
A0A0N4SVX9_MOUSE,
E9QL12_MOUSE
UniprotKB:
Q9ESD7,
E9Q423,
A0A0N4SUN3,
A0A0N4SUJ2,
E9PXU9,
A0A0N4SWH3,
A0A0N4SV63,
A0A0N4SVX9,
E9QL12
UniParc:
UPI0000F223CD,
UPI0003D77EBB,
UPI0000E7F778,
UPI0003D6F407,
UPI0003D71673,
UPI0003D6E7FC,
UPI0000F223CE,
UPI0003D70888,
UPI0000D8A853,
UPI000185D555,
UPI0000E56ED3
EMBL:
AF188290,
AJ242954,
AK131144,
BC043692,
AC153607,
AC153608
Ensembl:
ENSMUSG00000033788
KO:
mmu:26903
|
| Nucleutide sequences |
EMBL-CDS:
AAG17046.2,
BAD21394.1,
CAB63111.1,
AAH43692.1
Ensembl_TRS:
ENSMUST00000168387,
ENSMUST00000081904,
ENSMUST00000113818,
ENSMUST00000113823,
ENSMUST00000204987,
ENSMUST00000204354,
ENSMUST00000089595,
ENSMUST00000153860,
ENSMUST00000204591,
ENSMUST00000203695,
ENSMUST00000113821
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000132297,
ENSMUSP00000109449,
ENSMUSP00000080579,
ENSMUSP00000109454,
ENSMUSP00000144748,
ENSMUSP00000144705,
ENSMUSP00000087022,
ENSMUSP00000145518,
ENSMUSP00000144970,
ENSMUSP00000145292,
ENSMUSP00000109452
RefSeq:
NP_067444.2,
XP_006506245.1,
XP_006506231.1,
XP_006506227.1,
XP_006506236.1,
XP_006506230.1,
NP_001071162.1,
XP_006506226.1,
XP_006506237.1,
NP_001297081.1,
XP_006506234.1,
XP_017177083.1,
XP_006506239.1,
XP_006506244.1,
XP_006506229.1,
XP_006506238.1,
XP_006506242.1,
XP_006506228.1,
XP_030111267.1,
XP_006506235.1,
XP_006506232.1,
XP_006506233.1,
XP_006506246.1,
XP_006506241.1,
XP_006506247.1,
XP_006506240.1
|
| Others |
UniRef100:
UniRef100_A0A0N4SWH3,
UniRef100_E9PXU9,
UniRef100_E9Q423,
UniRef100_A0A0N4SUJ2,
UniRef100_E9QL12,
UniRef100_A0A0N4SV63,
UniRef100_A0A0N4SVX9,
UniRef100_A0A0N4SUN3,
UniRef100_Q9ESD7
UniRef90:
UniRef90_E9Q423,
UniRef90_Q9ESD7,
UniRef90_O75923,
UniRef90_O75923-13
UniRef50:
UniRef50_O75923
UniGene:
Mm.220982
CCDS:
CCDS39536.1,
CCDS85081.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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