| Type | Description |
|---|---|
| Definition | acyl-CoA thioesterase 1 |
| Date | Results | Publications |
|---|---|---|
| 2016-04-23 11:40:00 | These results suggest that ACOT1 has potential therapeutic values to protect heart from sepsis mediated dysfunction, possibly through activating PPARa/PGC1a signaling. | 26518651 |
| 2013-05-25 12:11:00 | ACOT1 plays a crucial protective role in the diabetic heart via PPARalpha/PGC1alpha signaling. | 23226270 |
| 2010-01-21 00:00:00 | Data show that Acot1 is under regulation by an interplay between hepatocyte nuclear factor 4alpha and peroxisome proliferator-activated receptor alpha. | 17485727 |
| Type | IDs |
|---|---|
| Synonymous | ACH2, CTE-1, CTE-I, Cte1, D12Ucla1 |
| Gene |
UniProtKB-ID:
ACOT1_MOUSE
UniprotKB:
O55137
UniParc:
UPI00000002CE
EMBL:
AF180795,
AF180794,
AF180793,
Y14004,
BC028261
Ensembl:
ENSMUSG00000072949
KO:
mmu:26897
|
| Nucleutide sequences |
EMBL-CDS:
AAF13870.1,
AAH28261.1,
CAA74327.1
Ensembl_TRS:
ENSMUST00000168120
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000126448
RefSeq:
NP_036136.1
|
| Others |
UniRef100:
UniRef100_O55137
UniRef90:
UniRef90_O55137
UniRef50:
UniRef50_Q9QYR7
UniGene:
Mm.1978
CCDS:
CCDS36487.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 28364022 |
EMBO Rep Jing Lu , Qing Xu , Ming Ji , Xiumei Guo , Xiaojiang Xu , David C Fargo , Xiaoling Li |
2017-05-01 | - |
| 27694478 |
FASEB J. Lina Zhou , Huifang Dai , Jian Wu , Mian Zhou , Hua Yuan , Juan Du , Lu Yang , Xiwei Wu , Hong Xu , Yuejin Hua , Jian Xu , Li Zheng , Binghui Shen |
2017-01-01 | - |
| 26518651 |
Biochem. Biophys. Res. Commun. Congying Xia , Ruolan Dong , Chen Chen , Hong Wang , Dao Wen Wang |
2015-12-25 |
Acot1
|
| 25209997 |
Elife Daniil Alpern , Diana Langer , Benoit Ballester , Stephanie Le Gras , Christophe Romier , Gabrielle Mengus , Irwin Davidson |
2014-09-10 | - |
| 22967998 |
Placental PPARγ regulates spatiotemporally diverse genes and a unique metabolic network. Dev. Biol. Tali Shalom-Barak , Xiaowen Zhang , Tianjiao Chu , W Timothy Schaiff , Janardan K Reddy , Jianming Xu , Yoel Sadovsky , Yaacov Barak |
2012-12-01 |
Hrct1,
Kcnj13,
Slc45a4,
Pkdcc,
Egln3,
Hsd17b11,
Aldoc,
Tpbpb,
Rnd2,
Cav1,
Clu,
Cxcr4,
Dgat1,
Sparcl1,
Emp2,
Epas1,
Epha4,
Fn1,
Gcgr,
Gcm1,
Ghrh,
Tsc22d3,
Gjb2,
Gm2a,
Hbegf,
Hpgd,
Hsd11b2,
Igfbp2,
Itk,
Ldhb,
Lepr,
Lifr,
Pdzd3,
Bbc3,
Maoa,
Mertk,
Mitf,
Mmp15,
Muc1,
Nfkb2,
Nid2,
Pcx,
Abcb1b,
Prkce,
Prl3b1,
Plat,
Pparg,
Ppargc1a,
Lgals3bp,
Prlr,
Pstpip1,
Ptger3,
Pthlh,
Rb1,
Scd2,
St8sia2,
Slc22a3,
Smpd1,
C2cd2,
Stc1,
Plekhh2,
Tgfb3,
Rnf144b,
Tpbpa,
Scgb1a1,
Vnn1,
Ywhaz,
Zfp185,
Vash2,
Megf9,
Tmem125,
Ncmap,
Sel1l3,
Eva1a,
Pxylp1,
Als2cl,
Nt5e,
Mab21l3,
Slc13a4,
Tmem255a,
Dcaf12l1,
Tceanc,
Vasn,
Map3k12,
Adck5,
Acot1,
Sgk2,
Nostrin,
L1td1,
Sgpp2,
Dppa5a,
Dkkl1,
Atp2a3,
Prdx4,
Irf6,
Ccrl2,
Rassf5,
St3gal6,
Car5b
|
| 23226270 |
Protective effects of Acyl-coA thioesterase 1 on diabetic heart via PPARα/PGC1α signaling. PLoS ONE Shenglan Yang , Chen Chen , Hong Wang , Xiaoquan Rao , Feng Wang , Quanlu Duan , Fuqiong Chen , Guangwen Long , Wei Gong , Ming-Hui Zou , Dao Wen Wang |
2012-01-01 |
Lepr,
Acot1,
Acot1
|
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 21267068 |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. Graciana Diez-Roux , Sandro Banfi , Marc Sultan , Lars Geffers , Santosh Anand , David Rozado , Alon Magen , Elena Canidio , Massimiliano Pagani , Ivana Peluso , Nathalie Lin-Marq , Muriel Koch , Marchesa Bilio , Immacolata Cantiello , Roberta Verde , Cristian De Masi , Salvatore A Bianchi , Juliette Cicchini , Elodie Perroud , Shprese Mehmeti , Emilie Dagand , Sabine Schrinner , Asja Nürnberger , Katja Schmidt , Katja Metz , Christina Zwingmann , Norbert Brieske , Cindy Springer , Ana Martinez Hernandez , Sarah Herzog , Frauke Grabbe , Cornelia Sieverding , Barbara Fischer , Kathrin Schrader , Maren Brockmeyer , Sarah Dettmer , Christin Helbig , Violaine Alunni , Marie-Annick Battaini , Carole Mura , Charlotte N Henrichsen , Raquel Garcia-Lopez , Diego Echevarria , Eduardo Puelles , Elena Garcia-Calero , Stefan Kruse , Markus Uhr , Christine Kauck , Guangjie Feng , Nestor Milyaev , Chuang Kee Ong , Lalit Kumar , MeiSze Lam , Colin A Semple , Attila Gyenesei , Stefan Mundlos , Uwe Radelof , Hans Lehrach , Paolo Sarmientos , Alexandre Reymond , Duncan R Davidson , Pascal Dollé , Stylianos E Antonarakis , Marie-Laure Yaspo , Salvador Martinez , Richard A Baldock , Gregor Eichele , Andrea Ballabio |
2011-01-18 | - |
| 18725516 |
Single-cell gene profiling defines differential progenitor subclasses in mammalian neurogenesis. Development Ayano Kawaguchi , Tomoko Ikawa , Takeya Kasukawa , Hiroki R Ueda , Kazuki Kurimoto , Mitinori Saitou , Fumio Matsuzaki |
2008-09-01 |
C230098O21Rik,
Aif1l,
Arx,
Neurod6,
Neurog2,
Serping1,
Ccna1,
Ccnb2,
Dab1,
Dcx,
Dll1,
Dll3,
Ednrb,
Eomes,
Slc17a6,
Fgfr2,
Fgfr3,
Fstl1,
Gli3,
Elavl2,
Elavl4,
Igfbp5,
Lrp8,
Lrrn3,
Mfge8,
Mfng,
Mki67,
Cited2,
Myt1,
Neurod1,
Nsg2,
Rpa2,
Cxcl12,
Sfrp2,
Slc1a3,
Sstr2,
Sox11,
Sox9,
Sdc3,
Sertad4,
Fam167a,
Vcam1,
AI504432,
Sorbs2,
Coro1c,
Gadd45g,
Mgat5b,
Ccnb1,
Lrrc16b,
Acot1,
Fkbp9,
Ndrg2,
Sybu,
Rasgef1b,
A730054J21Rik,
Insm1,
Hes6,
Olfm1,
Ttyh1,
Ppp1r1a,
Trp53inp1,
Rwdd3,
Soga3,
Ccdc80,
Nrn1,
Trp53inp2,
Ddah1,
Gpx8,
Afap1,
Uaca,
Clvs1,
9430087N24Rik
|
| 18614015 |
A mitochondrial protein compendium elucidates complex I disease biology. Cell David J Pagliarini , Sarah E Calvo , Betty Chang , Sunil A Sheth , Scott B Vafai , Shao-En Ong , Geoffrey A Walford , Canny Sugiana , Avihu Boneh , William K Chen , David E Hill , Marc Vidal , James G Evans , David R Thorburn , Steven A Carr , Vamsi K Mootha |
2008-07-11 |
Acacb,
Hscb,
Gadd45gip1,
Lars2,
Acad11,
Chchd10,
Nt5dc3,
Slc25a41,
Nt5m,
Cyp27a1,
Acly,
Ndufb11,
Gldc,
Rexo2,
Rars,
Aldh6a1,
Slc25a47,
Rdh14,
Ppif,
Ldhal6b,
Me2,
Glyat,
Slc25a45,
Acaca,
Nt5c3,
Mrpl10,
Mrpl41,
Mrpl30,
Aldh1l1,
Mthfs,
Shmt2,
Atic,
Mthfd1,
Mat2b,
Fam210a,
Gpt2,
Lyrm2,
Rdh13,
Mtrf1l,
Atad3a,
Rars2,
Sccpdh,
Me3,
Maob,
Dut,
Cyp11b1,
Fdps,
Akr7a5,
Msra,
Krt5,
Cox6b1,
Qdpr,
Acat1,
Acat2,
Aldh7a1,
Pcca,
Etfb,
Etfa,
Nudt19,
Acadl,
Acadm,
Acadvl,
Acaa1a,
Acads,
Aco1,
Aco2,
Prosc,
Afg3l1,
Adsl,
Agxt,
Ak2,
Ak4,
Akap1,
Alas1,
Alas2,
Abcd1,
Aldh2,
Aldh3a2,
Gfer,
Acsm1,
Slc25a4,
Slc25a5,
Prdx3,
Prdx6,
Mrps2,
Arg2,
Rhoa,
Atp5a1,
Atp5b,
Atp5c1,
Atp5f1,
Atp5g1,
Atp5j,
Atp5k,
Atpif1,
Auh,
Akr1b7,
Bad,
Bak1
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
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|---|---|---|
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