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268934 Grm4

268934

Grm4

glutamate receptor, metabotropic 4

protein-coding

Mus musculus

基因描述

Type Description
Definition glutamate receptor, metabotropic 4

研究结论

Date Results Publications
2017-10-14 11:22:00 This immuno-electron microscopic studies suggest that pre-synaptic metabotropic glutamate receptor 4 (mGluR4) in striatal glutamatergic terminals is expressed almost exclusively in cortical boutons to subserve regulatory influences upon a large contingent of corticostriatal terminals that preferentially target putative "indirect" pathway striatal projection neurons in mice. 26832920
2017-01-28 10:40:00 Study assessed the actions of the first mGlur4-selective orthosteric agonist, LSP4-2022, in several tests reflecting positive, negative, and cognitive symptoms of schizophrenia; results suggest that the interplay between mGlu4 and GABAB receptors may become the basis for a novel therapy for schizophrenic patients with predomination of positive symptoms 26769224
2016-03-12 11:23:00 Results offer the first evidence that changes in the striatal expression of mGlu4 and mGlu5 receptors occur in acute models of parkinsonisms 25747602
2015-12-05 10:13:00 Involvement of multiple taste receptors in umami taste: analysis of gustatory nerve responses in metabotropic glutamate receptor 4 knockout mice 25529865
2014-03-01 13:00:00 A functional hetero-complex is formed with mGluR2 and mGluR4 in central nervous system. 24381270

名称对应

Type IDs
Synonymous Gprc1d, mGluR4
Gene
UniProtKB-ID: GRM4_MOUSE, A0A140T8R6_MOUSE, G3XA00_MOUSE
UniprotKB: Q68EF4, A0A140T8R6, G3XA00
UniParc: UPI00015C73E0, UPI0000419FE6, UPI00015C73DF, UPI000024E605
EMBL: AC127341, BC080284, AY255558, BC072635
Ensembl: ENSMUSG00000063239
KO: mmu:268934
Nucleutide sequences
EMBL-CDS: AAH80284.1, AAO85070.1
Ensembl_TRS: ENSMUST00000118489, ENSMUST00000118161, ENSMUST00000231290
Protein sequencees
Ensembl_PRO: ENSMUSP00000112578, ENSMUSP00000113819, ENSMUSP00000156001
RefSeq: NP_001013403.1, NP_001366246.1, NP_001347121.1, XP_006524383.1, NP_001277974.1, XP_006524384.1, XP_030105688.1, XP_011244777.1
Others
UniRef100: UniRef100_Q68EF4, UniRef100_G3XA00, UniRef100_A0A140T8R6
UniRef90: UniRef90_Q68EF4-2, UniRef90_P31423
UniRef50: UniRef50_P70579, UniRef50_P31423
UniGene: Mm.358940
CCDS: CCDS70775.1, CCDS28563.1

全选

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