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268903 Nrip1

268903

Nrip1

nuclear receptor interacting protein 1

protein-coding

Mus musculus

基因描述

Type Description
Definition nuclear receptor interacting protein 1

研究结论

Date Results Publications
2020-09-12 16:05:00 Nuclear receptor co-repressor RIP140 regulates diurnal expression of cytochrome P450 2b10 in mouse liver. 32238093
2020-07-11 11:03:00 NRIP is essential to maintain sarcomere structure and mitochondrial/contractile function in cardiomyocytes. 31629737
2019-09-07 12:13:00 Deletion of Nrip1 can significantly extend longevity of female mice (log-rank test, p = .0004). We also found that Nrip1 expression is altered differently in various tissues during aging and under diet restriction. Remarkably, Nrip1 expression is elevated with aging in visceral white adipose tissue, but significantly reduced after 4 months of diet restriction. 29346516
2019-07-06 12:50:00 RIP140 expression in osteoclast precursors and its protein regulation are crucial for osteoclast differentiation, activity, and coupled bone formation. In mice, monocyte/macrophage-specific knockdown of RIP140 resulted in a cancellous osteopenic phenotype with significantly increased bone resorption and reduced bone formation. 28405613
2019-06-01 12:33:00 Disruption of a nuclear co-repressor of catabolism, the Nrip1 gene, in white adipocytes enhanced adipocyte browning with a marked increase of uncoupling protein 1 expression. 30190322

名称对应

Type IDs
Synonymous 6030458L20Rik, 8430438I05Rik, 9630050P12, AA959574, AW456757, RIP140
Gene
UniProtKB-ID: NRIP1_MOUSE
UniprotKB: Q8CBD1
UniParc: UPI0000026006
EMBL: AK156233, AK084498, BC060232, AF053062, AK036273
Ensembl: ENSMUSG00000048490
KO: mmu:268903
Nucleutide sequences
EMBL-CDS: AAC69611.1, BAE33634.1, BAC39197.1, AAH60232.1, BAC29368.1
Ensembl_TRS: ENSMUST00000121927, ENSMUST00000054178
Protein sequencees
Ensembl_PRO: ENSMUSP00000112959, ENSMUSP00000051726
RefSeq: XP_006523117.1, XP_017172509.1, NP_775616.1, XP_036015860.1, XP_006523113.1, NP_001345167.1
Others
UniRef100: UniRef100_Q8CBD1
UniRef90: UniRef90_Q8CBD1
UniRef50: UniRef50_P48552
UniGene: Mm.74711, Mm.455873
CCDS: CCDS28274.1

全选

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