| Type | Description |
|---|---|
| Definition | C-type lectin domain family 4, member a2 |
| Date | Results | Publications |
|---|---|---|
| 2018-04-14 10:36:00 | DCIR modulates immunity to M. tuberculosis through sustaining type I IFN signaling in DCs, which reduces IL-12-p70 production and Th1 expansion. As a consequence, DCIR-deficient mice control M. tuberculosis infection better than their WT counterparts but also develop more immunopathology in the lungs. | 28069953 |
| 2017-07-15 11:25:00 | this study shows that upon injection of d-galactosamine and lipopolysaccharide, Dcir1-/- mice show decreased mortality rates and serum levels of alanine aminotransferase | 28127756 |
| 2016-07-02 10:20:00 | Dcir1 enhances the pathogenesis of DSS colitis by altering neutrophil recruitment and their functions. | 26497661 |
| 2016-02-06 12:26:00 | While DCIR1 was ubiquitously expressed on myeloid cells in various immune organs, significant expression of DCAR2 was detected only on subpopulations of conventional dendritic cells from bone marrow and skin-draining lymph nodes. | 26431873 |
| 2015-11-14 10:31:00 | MCL-/- as well as DCIR-/- mice exhibited only a slightly increased severity of disease compared to wild-type mice indicating a limited role for MCL and DCIR in the regulation of intestinal immunity. | 25068517 |
| Type | IDs |
|---|---|
| Synonymous | Clec4a, Clecsf6, DCIR, Dcir1 |
| Gene |
UniProtKB-ID:
CLC4A_MOUSE,
Q923C7_MOUSE,
C6EQI8_MOUSE
UniprotKB:
Q9QZ15,
Q923C7,
C6EQI8
UniParc:
UPI0000025327,
UPI0001A8EAFA,
UPI00000233E0
EMBL:
AF387099,
AK049002,
BC096565,
AC164111,
BC075729,
AJ133533,
BC006623,
EU234028
Ensembl:
ENSMUSG00000030148
KO:
mmu:26888
|
| Nucleutide sequences |
EMBL-CDS:
BAC33509.1,
AAM22402.1,
AAH75729.1,
CAB57870.1,
AAH96565.1,
AAH06623.1,
ACD47050.1
Ensembl_TRS:
ENSMUST00000041779,
ENSMUST00000161365,
ENSMUST00000032248
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000124615,
ENSMUSP00000045781,
ENSMUSP00000032248
RefSeq:
XP_011239666.1,
NP_001163804.1,
NP_036129.1,
NP_001163803.1,
XP_006506218.1,
XP_030111263.1
|
| Others |
UniRef100:
UniRef100_Q923C7,
UniRef100_C6EQI8,
UniRef100_Q9QZ15
UniRef90:
UniRef90_Q9QZ15,
UniRef90_C6EQI8
UniRef50:
UniRef50_Q9UMR7,
UniRef50_C6EQI8
UniGene:
Mm.47384
CCDS:
CCDS20510.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员