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268860 Abat

268860

Abat

4-aminobutyrate aminotransferase

protein-coding

Mus musculus

基因描述

Type Description
Definition 4-aminobutyrate aminotransferase

研究结论

Date Results Publications
2019-12-07 10:12:00 These findings have provided underlying molecular details for the aggressive behavior of basal-like breast cancer (BLBC). The Snail-mediated downregulation of ABAT expression in BLBC provides tumorigenic and metastatic advantages by activating GABA-mediated Ca(2+)-NFAT1 axis. 30662552
2018-09-22 11:09:00 Propionate-mediated inhibition of neuronal GABA transaminase, an enzyme of the inner mitochondrial membrane, indicates entry of propionate into neuronal mitochondria.Propionate-induced inhibition of energy metabolism in GABAergic neurons may render the striatum, in which >90% of the neurons are GABAergic, particularly vulnerable to degeneration in propionic acidemia 29339464

名称对应

Type IDs
Synonymous 9630038C02Rik, AI255750, Gabaat, Gabat, Gm9851, I54, Laibat, X61497
Gene
UniProtKB-ID: GABT_MOUSE
UniprotKB: P61922
UniParc: UPI0000027731, UPI00001CDFD5
EMBL: BC058521, AK036128, BC058079
Ensembl: ENSMUSG00000057880
KO: mmu:268860
Nucleutide sequences
EMBL-CDS: BAC29312.1, AAH58521.1, AAH58079.1
Ensembl_TRS: ENSMUST00000065987, ENSMUST00000115839
Protein sequencees
Ensembl_PRO: ENSMUSP00000111505, ENSMUSP00000063548
RefSeq: NP_001164449.1, NP_766549.2
Others
UniRef100: UniRef100_P61922
UniRef90: UniRef90_P50554
UniRef50: UniRef50_P50554
UniGene: Mm.259315
CCDS: CCDS49754.1, CCDS27939.1

全选

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研究热度

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